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Your Good Partner in Biology Research

DOCK5 Antibody, Biotin conjugated

  • 中文名稱:
    DOCK5兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào):
    CSB-PA875689LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) DOCK5 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DOCK5
  • 別名:
    DOCK5Dedicator of cytokinesis protein 5 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Dedicator of cytokinesis protein 5 protein (1-200AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Along with DOCK1, mediates CRK/CRKL regulation of epithelial and endothelial cell spreading and migration on type IV collagen.
  • 基因功能參考文獻(xiàn):
    1. our work identifies DOCK5 as a key regulator of epithelial invasion and metastasis, and demonstrates that suppression of DOCK5 by GIT2 represents a previously unappreciated mechanism for coordination of Rho and Rac GTPases. PMID: 27669437
    2. the potential role of DOCK5 in human obesity PMID: 22595969
    3. along with DOCK1, DOCK5 is an important mediator of CrkII/CrkL regulation of Caco-2 spreading and migration on collagen IV. PMID: 19004829
  • 亞細(xì)胞定位:
    Cytoplasm. Cell membrane.
  • 蛋白家族:
    DOCK family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 23476

    OMIM: 616904

    KEGG: hsa:80005

    STRING: 9606.ENSP00000276440

    UniGene: Hs.195403



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