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  4. DNASE2B Antibody, HRP conjugated

DNASE2B Antibody, HRP conjugated

  • 中文名稱：
    DNASE2B兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA841227LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DNASE2B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DNASE2B
  • 別名：
    DNASE2B antibody; DLADDeoxyribonuclease-2-beta antibody; EC 3.1.22.1 antibody; DNase II-like acid DNase antibody; DNase2-like acid DNase antibody; Deoxyribonuclease II beta antibody; DNase II beta antibody; Endonuclease DLAD antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Deoxyribonuclease-2-beta protein (68-281AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Hydrolyzes DNA under acidic conditions. Does not require divalent cations for activity. Participates in the degradation of nuclear DNA during lens cell differentiation.
  • 基因功能參考文獻：
    1. HSF4 exerts its function on lens differentiation via positive regulation of DLAD expression. PMID: 23507146
    2. These data identify DNase 2 as the predominant DNase on the mammalian skin surface and indicate that its activity is primarily targeted to exogenous DNA. PMID: 21390259
    3. gene lie head-to-head with the urate oxidase gene PMID: 11700027
  • 亞細胞定位：
    Lysosome.
  • 蛋白家族：
    DNase II family
  • 組織特異性：
    Highly expressed in the eye lens and in salivary gland. Detected at lower levels in lung, prostate and lymph node. Isoform 2 is lung specific.
  • 數據庫鏈接：

    HGNC: 28875

    OMIM: 608057

    KEGG: hsa:58511

    STRING: 9606.ENSP00000359699

    UniGene: Hs.129142



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