在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DNAJC2 Antibody

DNAJC2 Antibody

  • 中文名稱：
    DNAJC2兔多克隆抗體
  • 貨號：
    CSB-PA858715ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA858715ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA858715ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DNAJC2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DNAJC2
  • 別名：
    AU020218 antibody; DnaJ (Hsp40) homolog subfamily C member 2 antibody; DnaJ homolog subfamily C member 2 antibody; Dnajc2 antibody; DNJC2_HUMAN antibody; M phase phosphoprotein 11 antibody; M-phase phosphoprotein 11 antibody; MGC105894 antibody; MIDA1 antibody; MPHOSPH11 antibody; MPP11 antibody; OTTMUSP00000031226 antibody; ZRF1 antibody; Zrf2 antibody; ZUO1 antibody; Zuotin related factor 1 antibody; Zuotin related factor 2 antibody; Zuotin-related factor 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human DnaJ homolog subfamily C member 2 protein (1-140AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, stimulates the ATPase activity of the ribosome-associated pool of Hsp70-type chaperones HSPA14 that bind to the nascent polypeptide chain. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation.
  • 基因功能參考文獻：
    1. These findings suggest that ZRF1 plays a crucial role in tumor malignant potential through its overexpression and highlight its usefulness as a prognostic factor and potential therapeutic target in gastric cancer PMID: 29228320
    2. Unexplored functions of ZRF1-mediated remodeling in replication and double strand break repair are discussed. PMID: 27599465
    3. ZRF1 mediates remodeling of this E3 ligase complex directly at the DNA lesion site. PMID: 27091446
    4. The antibody response to ZRF1 was higher in sera of patients with invasive ductal carcinoma than in sera of patients with other histological types of breast tumors. PMID: 27847402
    5. Zrf1 is transcriptional regulator of neural fate downstream of Id1 in embryonic stem cells.During embryonic stem cell differentiation, Id1 levels decrease allowing Zrf1 to activate neural genes. PMID: 25361733
    6. our data reveal that ZRF1 is a key transcriptional regulator in leukemia progression PMID: 24292673
    7. Zrf1 plays an essential role in neural progenitor cell generation and maintenance PMID: 24449271
    8. ZRF1 regulates the INK4-ARF locus during cellular proliferation and senescence, and alterations in ZRF1 may contribute to tumorigenesis. PMID: 22733129
    9. the majority of AML patients elicited a humoral immune response against the tumor antigen MPP11 PMID: 22433847
    10. describe a novel epitope derived from the MPP11 antigen that has been recognized by human CD8+ CTL PMID: 20231810
    11. At the onset of differentiation, ZRF1 specifically displaces polycomb-repressive complex 1 (PRC1) from chromatin and facilitates transcriptional activation PMID: 21179169
    12. concluded that Mpp11, an ortholog of yeast Zuo, is a ribosome-associated J protein; proposed that in metazoans, ribosome-associated Zuo and Mpp11 orthologs recruit cytosolic Hsc70 to short ribosome-bound nascent chains as they exit the ribosome PMID: 15802566
    13. MPP11 is localized to the cytosol and with Hsp70L1, forms the mammalian ribosome-associated complex. PMID: 16002468

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm, cytosol.
  • 組織特異性：
    Widely expressed.
  • 數據庫鏈接：

    HGNC: 13192

    OMIM: 605502

    KEGG: hsa:27000

    STRING: 9606.ENSP00000368565

    UniGene: Hs.558476



主站蜘蛛池模板： 国产乱人无码伦av在线a| 日本乱妇乱子视频| 亚洲精品无播放器在线播放| 内射老妇bbwx0c0ck| 女人被黑人躁得好爽视频| 精品国产福利在线视频| 国产精品偷伦视频观看免费| 免费中文熟妇在线影片| 在线观看国产精品电影| 久久亚洲道色综合久久| 亚洲乱码伦av| 少妇激情一区二区三区视频小说| 香港三级韩国三级日本三级| 国产麻豆精品传媒av国产婷婷| 精品国偷自产在线视频99| 亚洲日本va中文字幕久久| 欧美亚洲一区二区三区| 国产精品国产三级国产av麻豆| 日本一卡二卡3卡四卡网站精品 | 7777精品伊人久久久大香线蕉| 男女同房做爰爽免费| 手机看片精品国产福利| 九九热爱视频精品视频| 国产女同疯狂作爱系列| 精品国产你懂的在线观看| 亚洲精品国产高清一线久久| 一本一道久久综合狠狠老| 日韩欧美一中文字暮专区| 亚洲综合另类小说色区色噜噜 | 大胆欧美熟妇xx| 日本japanese丰满白浆 | 伊人狠狠色丁香婷婷综合| 免费国产成人午夜福利电影| 亚洲午夜精品久久久久久浪潮 | 天堂中文在线最新版地址| 久久99精品久久久久久| 亚洲中文字幕在线第二页| 国产成人av在线影院无毒| 久久精品国产欧美日韩| 色偷拍 自怕 亚洲 10p| 日韩国产亚洲一区二区三区|