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  4. DNAJC12 Antibody

DNAJC12 Antibody

  • 中文名稱：
    DNAJC12兔多克隆抗體
  • 貨號：
    CSB-PA007019GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DNAJC12
  • 別名：
    DJC12_HUMAN antibody; DnaJ (Hsp40) homolog subfamily C member 12 antibody; DnaJ heat shock protein family (Hsp40) member C12 antibody; DnaJ homolog subfamily C member 12 antibody; DnaJ/Hsp40 homolog; subfamily C; member 12 antibody; DNAJC12 antibody; HPANBH4 antibody; J domain containing protein 1 (JDP1) antibody; J domain containing protein 1 antibody; J domain protein 1 antibody; J domain-containing protein 1 antibody; JDP1 antibody; mJDP1 antibody; RP11-57G10.2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human DNAJC12
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. Molecular diagnostics for DNAJC12 variants are thus mandatory in all patients in which deficiencies of PAH and BH4 are genetically excluded. PMID: 29174366
    2. DNAJC12 mutation is not a risk factor of Parkinson's disease in Chinese Han population. PMID: 29801756
    3. The results of this study suggest that DNAJC12 mutations (absent in 500 early-onset patients with Parkinson's disease) rarely cause dopa-responsive nonprogressive parkinsonism in adulthood. PMID: 28892570
    4. We report biallelic mutations of DNAJC12 in six affected individuals from four families with hyperphenylalaninemia and dopamine and serotonin deficiencies not caused by mutations in phenylalanine hydroxylase or any known tetrahydrobiopterin metabolism genes. PMID: 28132689
    5. High expression of DNAJC12 correlates with poor prognosis for rectal cancer. PMID: 25805104
    6. the endogenous DNAJC12 and Hsc70 proteins interact in LNCaP cells. PMID: 24122553
    7. JDP1 is a estrogen target gene and that its expression might be used as a marker of the estrogen transactivation activity PMID: 16391838

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  • 相關疾?。?/div>
    Hyperphenylalaninemia, mild, non-BH4-deficient (HPANBH4)
  • 亞細胞定位：
    [Isoform a]: Cytoplasm.
  • 組織特異性：
    Expressed at high levels in brain, heart, and testis, and at reduced levels in kidney and stomach.
  • 數據庫鏈接：

    HGNC: 28908

    OMIM: 606060

    KEGG: hsa:56521

    STRING: 9606.ENSP00000225171

    UniGene: Hs.260720



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