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  4. DMRT3 Antibody

DMRT3 Antibody

  • 中文名稱：
    DMRT3兔多克隆抗體
  • 貨號：
    CSB-PA885692LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA885692LA01HU diluted at 1:700 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DMRT3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DMRT3
  • 別名：
    DMRT3 antibody; DMRTA3Doublesex- and mab-3-related transcription factor 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Doublesex- and mab-3-related transcription factor 3 protein (92-224AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，DMRT3 Antibody (CSB-PA885692LA01HU)，的標記方式是Non-conjugated。對于DMRT3 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA885692LB01HU DMRT3 Antibody, HRP conjugated ELISA
    FITC CSB-PA885692LC01HU DMRT3 Antibody, FITC conjugated
    Biotin CSB-PA885692LD01HU DMRT3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:500-1:1000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Probable transcription factor that plays a role in configuring the spinal circuits controlling stride in vertebrates. Involved in neuronal specification within specific subdivision of spinal cord neurons and in the development of a coordinated locomotor network controlling limb movements. May regulate transcription during sexual development.
  • 基因功能參考文獻：
    1. Thus, the deletion of the cis-regulatory element for DMRT3 in humans may cause impaired development of the forebrain and gait abnormalities, resulting in spastic CP. In conclusion, this study provides new mechanistic insights into the genetic basis of CP. PMID: 29305858
    2. Chromosome 9p loss is the hallmark of squamous cell carcinoma, and DMRT1, DMRT3 and DOCK8 genes at 9p24.3 might be of interest for the study of the pathophysiology of SCC as potential targets for therapeutic measures. PMID: 20596660
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    DMRT family
  • 組織特異性：
    Expressed in testis.
  • 數據庫鏈接：

    HGNC: 13909

    OMIM: 614754

    KEGG: hsa:58524

    UniGene: Hs.189174



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