在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DLG2 Antibody

  • 中文名稱:
    DLG2兔多克隆抗體
  • 貨號:
    CSB-PA007803
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of 293T-UV cells using PSD-93 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    Channel associated protein of synapse 110 antibody; Channel associated protein of synapses 110kD antibody; Channel-associated protein of synapse-110 antibody; Chapsyn 110 antibody; Chapsyn-110 antibody; Chapsyn110 antibody; Discs; large homolog 2 (Drosophila) antibody; Disks large homolog 2 antibody; DKFZp781D1854 antibody; DKFZp781E0954 antibody; Dlg 2 antibody; dlg2 antibody; DLG2_HUMAN antibody; Dlgh 2 antibody; Dlgh2 antibody; FLJ37266 antibody; Gm1197 antibody; MGC131811 antibody; Postsynaptic density protein PSD 93 antibody; Postsynaptic density protein PSD-93 antibody; Postsynaptic density protein PSD93 antibody; PSD 93 antibody; PSD93 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human PSD-93.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.
  • 基因功能參考文獻:
    1. DLG2 influenced the risk of Parkinson disease in Taiwan. PMID: 29290481
    2. Two novel promoters and coding first exons in the DLG2 gene were identified. These novel isoforms are expressed in the fetal brain. Deletions of these new elements were found associated with neurodevelopmental disorders. The work brings evidence for the lack of cross-annotation in human versus mouse reference genomes and nucleotide versus protein databases. PMID: 28724449
    3. DLG2 - novel candidate genes validated in a large case-control sample of schizophrenia. PMID: 26460480
    4. The PDZ1 domain of PSD-93 might accept peptides with larger residues at the C-terminus than that of PSD-95, for example the GluD2 C-terminal Ile versus the Val found at the C-terminus of NMDA receptors. PMID: 23519667
    5. This study showed that DLG2 is related the complex learning. PMID: 23201973
    6. Comparison of the structures of the binding cleft of PSD-93 PDZ1 with the previously reported structures of PSD-93 PDZ2 and PDZ3 as well as of the closely related human PSD-95 PDZ1 shows that they are very similar in terms of amino-acid composition PMID: 20054121
    7. Variation at the DLG2 locus contributes to maintenance of glucose homeostasis through regulation of insulin sensitivity and beta-cell function. PMID: 19931931
    8. Coexpression of Kir2.1 and PSD-93delta had no discernible effect upon channel kinetics but resulted in cell surface Kir2.1 clustering and suppression of channel internalization. PMID: 15304517
    9. identifies new isoform of DLG2 gene, which contains 3'-end exons of the known DLG2 gene along with the hypothetical gene FLJ37266; new isoform is specifically upregulated in renal oncocytoma PMID: 16640776
    10. postsynaptic density-93 and N-methyl-D-aspartate receptors subunits 2B mRNA are upregulated in temporal lobe tissue of epilepsy PMID: 17506987

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor. Cell junction, synapse, postsynaptic density. Cell junction, synapse. Membrane. Cell projection, axon. Perikaryon.
  • 蛋白家族:
    MAGUK family
  • 數據庫鏈接:

    HGNC: 2901

    OMIM: 603583

    KEGG: hsa:1740

    STRING: 9606.ENSP00000365272

    UniGene: Hs.367656



主站蜘蛛池模板: 国产熟女精品视频大全| 日本真人边吃奶边做爽动态图| 日本一区二区无卡高清视频| 人妻丰满av无码中文字幕| 欧美人与动性xxxxbbbb| av无码欧洲亚洲电影网| 一本加勒比波多野结衣| 成年丰满熟妇午夜免费视频 | 无码少妇一区二区三区浪潮av| 精品熟女少妇av久久免费软件 | 国产精品亚洲专区无码唯爱网 | 国产免费艾彩sm调教视频| 一本色道久久88综合日韩精品| 国产成人无码a区视频| 中国少妇初尝黑人巨高清| 国产欧美另类久久久精品不卡| 欧美寡妇xxxx黑人猛交| 日韩熟女精品一区二区三区| 强插女教师av在线| 亚洲视频无码高清在线| 国产成年女人毛片80s网站| 免费无码毛片一区二区三区a片| 欧洲亚洲色一区二区色99| 亚洲欧洲日产国码在线| 中文字幕+乱码+中文乱码www| 天天躁夜夜躁狠狠躁2021a2| 欧美日韩亚洲国产精品| 久久久亚洲精华液精华液精华液| 中文字幕无码av正片| 97无码免费人妻超级碰碰碰碰| 国产成人精品av| 2021无码最新国产在线观看| 国产偷伦视频片免费视频| 人人爽久久久噜噜噜婷婷| 国产精品久久久久久久久鸭| 午夜成人理论福利片| 国产男生午夜福利免费网站| 国产精品青青青高清在线| 日本一区二区三区免费播放| 亚洲中文字幕无码一区二区三区| 成在人线av无码免观看|