在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DLAT Antibody
  • 中文名稱：
    DLAT兔多克隆抗體
  • 貨號：
    CSB-PA006926LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: HepG2 whole cell lysate
      All lanes: DLAT antibody at 4μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 69 kDa
      Observed band size: 69 kDa
    • Immunoprecipitating DLAT in HepG2 whole cell lysate
      Lane 1: Rabbit control IgG instead of CSB-PA006926LA01HU in HepG2 whole cell lysate. For western blotting, a HRP-conjugated Protein G antibody was used as the secondary antibody (1/2000)
      Lane 2: CSB-PA006926LA01HU (6μg) + HepG2 whole cell lysate (1mg)
      Lane 3: HepG2 whole cell lysate (20μg)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DLAT Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DLAT
  • 別名：
    70 kDa mitochondrial autoantigen of primary biliary cirrhosis antibody; Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex antibody; Dihydrolipoamide S Acetyltransferase antibody; Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex antibody; dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex mitochondrial antibody; DLAT antibody; DLTA antibody; E2 antibody; E2 component of pyruvate dehydrogenase complex antibody; M2 antigen complex 70 kDa subunit antibody; mitochondrial antibody; ODP2_HUMAN antibody; PBC antibody; PDC E2 antibody; PDC-E2 antibody; PDCE2 antibody; Pyruvate dehydrogenase complex component E2 antibody; Pyruvate dehydrogenase complex E2 subunit antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial protein (26-217AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，DLAT Antibody (CSB-PA006926LA01HU)，的標(biāo)記方式是Non-conjugated。對于DLAT Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA006926LB01HU DLAT Antibody, HRP conjugated ELISA
    FITC CSB-PA006926LC01HU DLAT Antibody, FITC conjugated
    Biotin CSB-PA006926LD01HU DLAT Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IP
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IP 1:200-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
  • 基因功能參考文獻(xiàn)：
    1. DLAT interacts with C1QBP in mitochondria. PMID: 26753982
    2. ongoing activation of PDCE2-specific B-cells in primary biliary cirrhosis PMID: 25043065
    3. Results show that DLAT and ACAT2 as upstream acetyltransferases of K76 and K294 in 6PGD protein. PMID: 25042803
    4. These findings were used to identify potentially antigenic sequences within PDC-E2 (an important hepatic autoantigen) that contain a DR0801 motif. PMID: 23543758
    5. Solution structure and characterisation of the human pyruvate dehydrogenase complex core assembly PMID: 20361979
    6. Data suggest that the catalytic site of pyruvate dehydrogenase complex E2 rather than the previously reported lipoyl binding peptide may contain immunodominant epitopes recognized by antimitochondrial antibodies in primary biliary cirrhosis. PMID: 20180236
    7. a novel HLA-A*0201-restricted epitope PDC-E2 165 to 174 was defined in patients with primary biliary cirrhosis. PMID: 12395322
    8. study of facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase PMID: 12816949
    9. model of the pyruvate dehydrogenase complex formed by E2 and E2 plus the E3-binding protein and binding of the E1 and E3 components PMID: 14638692
    10. Having found that there is an excellent and almost unique match between the PDC-E2 autoepitope and a sequence in mycobacterial hsp65s, we tested the corresponding peptides for cross-reactivity using sera from 90 Spanish and British PBC patients. PMID: 15120760
    11. This study report two unrelated patients with pyruvate dehydrogenase deficiency caused by defects in the E2 subunit. PMID: 16049940
    12. epitope specificity of these PDC-E2 autoantibodies was distinctive suggesting that the mechanisms leading to loss of tolerance in the transplantation patients are distinct from primary biliary cirrhosis PMID: 17068145
    13. Species specificity in the interaction between hE1beta and hE2 in pyruvate dehydrogenase complex. PMID: 18206651
    14. tissue specificity of the autoimmune injury in primary biliary cirrhosis is a consequence of the unique characteristics of HIBECs during apoptosis and can be explained by exposure to immune system of intact immunoreactive PDC-E2 within apoptotic blebs. PMID: 19185000

    顯示更多

    收起更多

  • 相關(guān)疾?。?/div>
    Pyruvate dehydrogenase E2 deficiency (PDHE2 deficiency)
  • 亞細(xì)胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    2-oxoacid dehydrogenase family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2896

    OMIM: 245348

    KEGG: hsa:1737

    STRING: 9606.ENSP00000280346

    UniGene: Hs.335551



主站蜘蛛池模板： 国产99爱在线视频免费观看| 国产精品av在线| 免费无码黄网站在线看| 一本一本久久a久久精品综合| 久久久受www免费人成| 亚洲欧洲日产最新| 久久精品免视看国产成人| 亚洲欧美成人片在线观看| 国产又色又刺激高潮视频| 一本久久精品一区二区| 久久aaaa片一区二区| 欧美金妇欧美乱妇xxxx| 美女把尿囗扒开让男人添| 粗大的内捧猛烈进出看视频| 人体内射精一区二区三区| 午夜性刺激免费看视频| 国产极品美女高潮抽搐免费网站| 香蕉噜噜噜噜私人影院| 午夜免费啪在线观看视频| 国产亚洲精品成人aa片新蒲金| 久久这里只精品国产免费10| 四虎国产精品永久免费网址 | 亚洲成aⅴ人片久青草影院| 成人无码av一区二区三区| 国产精品无码dvd在线观看| 成人性生交大片免费看中文| 99精品久久99久久久久| 国产99在线 | 免费| av第一福利网站| √天堂8资源中文在线| 和岳每晚弄的高潮嗷嗷叫视频| 国产日产精品久久快鸭的功能介绍 | 最新 国产 精品 精品 视频| 国产精品一区二区久久不卡| 扒开双腿吃奶呻吟做受视频| 亚洲成a人片77777国产| 国产精品欧美成人| 啦啦啦www播放日本观看| 亚洲欧美日韩国产成人| 久久国内精品自在自线观看| 欧美乱码卡一卡二卡三新区|