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  4. DIS3L Antibody

DIS3L Antibody

  • 中文名稱：
    DIS3L兔多克隆抗體
  • 貨號：
    CSB-PA823476LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: DIS3L antibody at 6µg/ml + MCF-7 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 121, 106, 87, 112 kDa
      Observed band size: 121 kDa
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA823476LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA823476LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DIS3L Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DIS3L
  • 別名：
    DIS3L antibody; DIS3L1 antibody; KIAA1955DIS3-like exonuclease 1 antibody; EC 3.1.13.- antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human DIS3-like exonuclease 1 protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，DIS3L Antibody (CSB-PA823476LA01HU)，的標記方式是Non-conjugated。對于DIS3L Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA823476LB01HU DIS3L Antibody, HRP conjugated ELISA
    FITC CSB-PA823476LC01HU DIS3L Antibody, FITC conjugated
    Biotin CSB-PA823476LD01HU DIS3L Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events. In the cytoplasm, the RNA exosome complex is involved in general mRNA turnover and specifically degrades inherently unstable mRNAs containing AU-rich elements (AREs) within their 3' untranslated regions, and in RNA surveillance pathways, preventing translation of aberrant mRNAs. It seems to be involved in degradation of histone mRNA.
  • 基因功能參考文獻：
    1. Data indicate that hDis3L1 is a novel exosome-associated exoribonuclease in the cytoplasm of human cells. PMID: 20531389
    2. Data show that hDIS3 and hDIS3L are active exonucleases, but only hDIS3 has retained endonucleolytic activity, and suggest that three different ribonucleases can serve as catalytic subunits for the exosome in human cells. PMID: 20531386
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    RNR ribonuclease family
  • 數據庫鏈接：

    HGNC: 28698

    OMIM: 614183

    KEGG: hsa:115752

    STRING: 9606.ENSP00000321711

    UniGene: Hs.446251



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