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  4. DHTKD1 Antibody

DHTKD1 Antibody

  • 中文名稱：
    DHTKD1兔多克隆抗體
  • 貨號：
    CSB-PA842685ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: DHTKD1 antibody at 1.82µg/ml
      Lane 1: Mouse heart tissue
      Lane 2: A431 whole cell lysate
      Lane 3: MCF-7 whole cell lysate
      Lane 4: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 103 kDa
      Observed band size: 103 kDa
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA842685ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA842685ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) DHTKD1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DHTKD1
  • 別名：
    AMOXAD antibody; CMT2Q antibody; Dehydrogenase E1 and transketolase domain containing 1 antibody; Dehydrogenase E1 and transketolase domain containing protein 1 antibody; Dehydrogenase E1 and transketolase domain-containing protein 1 antibody; DHTK1_HUMAN antibody; dhtkd1 antibody; DKFZp762M115 antibody; KIAA1630 antibody; MGC3090 antibody; Probable 2 oxoglutarate dehydrogenase E1 component DHKTD1 mitochondrial antibody; Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1; mitochondrial antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial protein (1-280AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3).
  • 基因功能參考文獻：
    1. DHTKD1 encodes the E1 subunit of the alpha-ketoadipic acid dehydrogenase complex PMID: 25860818
    2. DHTKD1 contributes to mitochondrial biogenesis and function maintenance. PMID: 24076469
    3. DHTKD1 mutations cause 2-aminoadipic and 2-oxoadipic aciduria. PMID: 23141293
    4. A nonsense mutation in DHTKD1 causes Charcot-Marie-Tooth disease type 2 in a large Chinese pedigree. PMID: 23141294
  • 相關疾病：
    Charcot-Marie-Tooth disease 2Q (CMT2Q); 2-aminoadipic 2-oxoadipic aciduria (AMOXAD)
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Alpha-ketoglutarate dehydrogenase family
  • 數據庫鏈接：

    HGNC: 23537

    OMIM: 204750

    KEGG: hsa:55526

    STRING: 9606.ENSP00000263035

    UniGene: Hs.104980



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