在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DHH Antibody

  • 中文名稱:
    DHH兔多克隆抗體
  • 貨號:
    CSB-PA006851LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunofluorescence staining of A549 cells with CSB-PA006851LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DHH Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    C78960 antibody; Desert hedgehog (Drosophila) homolog antibody; Desert hedgehog antibody; Desert hedgehog homolog (Drosophila) antibody; Desert hedgehog protein C-product antibody; Desert hedgehog protein precursor antibody; DHH antibody; DHH_HUMAN antibody; GDXYM antibody; HHG-3 antibody; Hira antibody; SRXY7 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Desert hedgehog protein (51-158AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,DHH Antibody (CSB-PA006851LA01HU),的標記方式是Non-conjugated。對于DHH Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA006851LB01HU DHH Antibody, HRP conjugated ELISA
    FITC CSB-PA006851LC01HU DHH Antibody, FITC conjugated
    Biotin CSB-PA006851LD01HU DHH Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Intercellular signal essential for a variety of patterning events during development. May function as a spermatocyte survival factor in the testes. Essential for testes development.
  • 基因功能參考文獻:
    1. Whole-exome sequencing revealed a homozygous variant in DHH leading to the p.Trp173Cys substitution. The relevant Trp residue is conserved, and its alteration was predicted to be deleterious. Molecular dynamics simulations showed that the mutation increases the conformational flexibility of the protein PMID: 28708305
    2. Single nucleotide polymorphism in the DHH gene is associated with bipolar disorder. PMID: 25517604
    3. Mutations in DHH play a role in 46,XY gonadal dysgenesis and are associated with seminoma formation and a neuropathy with minifascicle formation. PMID: 25927242
    4. Findings are unprecedented and indicate that the DHH-RHEBL1 fusion transcript is a novel recurrent feature in the changing landscape of CBFA2T3-GLIS2-positive childhood AML. PMID: 24127550
    5. Mutations in DHH are associated with 46,XY pure gonadal dysgenesis and mixed gonadal dysgenesis. PMID: 23786321
    6. This study demonistrated that Desert hedgehog links transcription factor Sox10 to peripheral nerve development. PMID: 22514309
    7. Studies indicate that pathways of Hedgehog (Hh), Wnt and Notch, which regulate development during embryonic life and somatic stem cells (SCs) in the adult organism, can be reactivated in malignancies and support tumor-initiating cells (TIC) scompartment. PMID: 22123293
    8. Two cases have been described in Indian patients with 46,XY complete gonadal dysgenesis that could be attributable to mutations in the Desert hedgehog (DHH) gene leading to non-functional DHH protein. PMID: 21816240
    9. We found no significant correlation between the expression of SOX9 and desert hedgehog, and neither SOX9 nor desert hedgehog expression was correlated to the histoprognostic grade in sarcomas. PMID: 21193222
    10. These data demonstrate that DHH is a key molecule in both male gonadal differentiation and perineurial formation in peripheral nerves PMID: 11990454
    11. Importance of DHH in mammalian male sexual differentiation, providing extended evidence that DHH constitutes a key gene in gonadal differentiation PMID: 16390857
    12. its signal transduction regulates tumor development. (review) PMID: 18788453
    13. Hh signaling is important in the pathogenesis of B-CLL and, hence, may be a potential therapeutic target PMID: 19074837

    顯示更多

    收起更多

  • 相關疾病:
    Partial gonadal dysgenesis with minifascicular neuropathy 46,XY (PGD); 46,XY sex reversal 7 (SRXY7)
  • 亞細胞定位:
    [Desert hedgehog protein N-product]: Cell membrane; Lipid-anchor; Extracellular side.; [Desert hedgehog protein C-product]: Secreted, extracellular space.
  • 蛋白家族:
    Hedgehog family
  • 數據庫鏈接:

    HGNC: 2865

    OMIM: 233420

    KEGG: hsa:50846

    STRING: 9606.ENSP00000266991

    UniGene: Hs.524382



主站蜘蛛池模板: 免费观看性欧美大片无片| 国产成人av在线影院| 亚洲 精品 综合 精品 自拍| 人妻换人妻仑乱| 天堂av男人在线播放| 久久久久免费看成人影片| 在线播放十八禁视频无遮挡| 国产xxx视频在线观看软件| 公与淑婷厨房猛烈进出视频免费 | 一色屋精品视频在线观看| 国产草莓精品国产av片国产| 午夜成人无码片在线观看影院| 太深太粗太爽太猛了视频免费观看| 国产在线精品一区二区三区| 亚洲熟妇无码av在线播放| 精品国产免费一区二区三区香蕉 | 99在线精品免费视频| 真人做受试看120分钟小视频| 欧美成人精品 一区二区三区| 欧美白丰满老太aaa片| 窝窝午夜色视频国产精品破| 成人午夜精品无码区| 亚洲 综合 欧美在线视频| 国产乱子伦一区二区三区四区五区| 熟女视频一区二区在线观看| 亚洲三区在线观看无套内射| 国产精品怡红院在线观看| 精品国产亚洲午夜精品av | 999久久久无码国产精品| 中文字幕有码无码av| 欧洲国产伦久久久久久久| 成人综合婷婷国产精品久久| 日本道免费精品一区二区| 国产 | 欧洲野花视频天堂视频p| 特级aaaaaaaaa毛片免费视频| 精品人妻伦一二三区久久| 国产精品人妻久久毛片高清无卡 | 亚洲精品久久午夜麻豆| 亚洲精品一区| 自慰系列无码专区| 无码专区手机在线播放|