DENND2D Antibody
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中文名稱：DENND2D兔多克隆抗體
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貨號：CSB-PA887987LA01HU
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規(guī)格：￥440
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圖片：
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Western blot
All lanes: DENND2D antibody at 4µg/ml + MCF-7 whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 54 kDa
Observed band size: 54 kDa -
Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA887987LA01HU at dilution of 1:100
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其他：
產(chǎn)品詳情
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產(chǎn)品名稱：Rabbit anti-Homo sapiens (Human) DENND2D Polyclonal antibody
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Uniprot No.：
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基因名：DENND2D
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別名：2010308M01Rik antibody; AI451421 antibody; DEN2D_HUMAN antibody; DENN domain containing 2D antibody; DENN domain-containing protein 2D antibody; DENN/MADD domain containing 2D antibody; DENND2D antibody; FLJ22457 antibody; MGC6915 antibody; RGD1305120 antibody; RP5-1180E21.2 antibody
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宿主：Rabbit
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反應(yīng)種屬：Human
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免疫原：Recombinant Human DENN domain-containing protein 2D protein (1-233AA)
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免疫原種屬：Homo sapiens (Human)
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標(biāo)記方式：Non-conjugated
本頁面中的產(chǎn)品，DENND2D Antibody (CSB-PA887987LA01HU)，的標(biāo)記方式是Non-conjugated。對于DENND2D Antibody，我們還提供其他標(biāo)記。見下表：
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克隆類型：Polyclonal
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抗體亞型：IgG
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純化方式：>95%, Protein G purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式：Liquid
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應(yīng)用范圍：ELISA, WB, IHC
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推薦稀釋比：
Application Recommended Dilution WB 1:500-1:2000 IHC 1:20-1:200 -
Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產(chǎn)品評價
相關(guān)產(chǎn)品
靶點詳情
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功能：Guanine nucleotide exchange factor (GEF) which may activate RAB9A and RAB9B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form.
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基因功能參考文獻(xiàn)：
- resulted in increased cell motility and invasive ability. Moreover, miR-1246 increased cell motility by directly targeting DENN/MADD Domain Containing 2D (DENND2D) PMID: 27929118
- Higher frequency of promoter hypermethylation of DENND2D is associated with gastric cancer. PMID: 24695972
- DENND2D is a candidate tumor suppressor gene that was inactivated by promoter hypermethylation in patients with esophageal squamous cell carcinoma and may serve as a novel biomarker of esophageal squamous cell carcinoma. PMID: 24317529
- DENND2D is a candidate tumor suppressor gene that is inactivated by promoter hypermethylation in patients with Hepatocellular carcinoma and may serve as a novel biomarker of early recurrence of Hepatocellular carcinoma . PMID: 24189587
- Our data show that DENND2D might function as a tumor suppressor-like gene, preventing survival and expansion of cells with genetic damage through apoptosis mechanism. Absence of DENND2D might play a permissive role, as an early event, in tumorigenesis. PMID: 23182661
- Mutations in DENND2D in melanoma by inhibition of nonsense-mediated mRNA decay. PMID: 18677770
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亞細(xì)胞定位：Cytoplasm.
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組織特異性：In bronchial mucosa, mainly expressed in ciliated and basal epithelial cells and weakly in alveolar cells (at protein level). Tends to be down-regulated in lung cancers, immortalized bronchial epithelial cell lines and precancerous lesions.
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數(shù)據(jù)庫鏈接：
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