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  4. DDX24 Antibody

DDX24 Antibody

  • 中文名稱：
    DDX24兔多克隆抗體
  • 貨號：
    CSB-PA040035
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    DDX24
  • 別名：
    ATP dependent RNA helicase DDX24 antibody; ATP-dependent RNA helicase ddx24 antibody; DDX 24 antibody; ddx24 antibody; DDX24_HUMAN antibody; DEAD (Asp Glu Ala Asp) box polypeptide 24 antibody; DEAD box protein 24 antibody; DEAD/H (Asp Glu Ala Asp) box polypeptide 24 antibody; S. cerevisiae CHL1 like helicase antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human DDX24.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    ATP-dependent RNA helicase.
  • 基因功能參考文獻：
    1. DDX24 is a negative regulator of p53 transcriptional activity.DDX24 inhibits p300 mediated acetylation of p53. PMID: 25867071
    2. depletion of DDX24 in cells impaired pre-rRNA processing and resulted both in abrogation of MDM2 function and in consequent p53 stabilization PMID: 24980433
    3. knockdown of a DEAD-box protein named DDX24 inhibits the packaging of HIV-1 RNA and thus diminishes viral infectivity. PMID: 18289627
  • 蛋白家族：
    DEAD box helicase family, DDX24/MAK5 subfamily
  • 組織特異性：
    Ubiquitous. Most abundant in heart and brain, but with lowest levels in thymus and small intestine.
  • 數據庫鏈接：

    HGNC: 13266

    OMIM: 606181

    KEGG: hsa:57062

    STRING: 9606.ENSP00000328690

    UniGene: Hs.510328



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