在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DDOST Antibody

  • 中文名稱:
    DDOST兔多克隆抗體
  • 貨號:
    CSB-PA006594GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    DDOST; KIAA0115; OST48; OK/SW-cl.45; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit; DDOST 48 kDa subunit; Oligosaccharyl transferase 48 kDa subunit
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human DDOST
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains. Required for the assembly of both SST3A- and SS3B-containing OST complexes. Required for efficient N-glycosylation.; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. Required for the assembly of both SST3A- and SS3B-containing OST complexes.
  • 基因功能參考文獻:
    1. DDOST and SIRT1 are differently expressed in peripheral blood mononuclear cells from type 1 diabetes patients with and without microvascular complications. Their expression is also influenced by dietary advanced glycation end-products and by statins and angiotensin receptor blockers. PMID: 29027826
    2. the cell-cycle-dependent post-translation modification of TREX1 regulates its interaction with OST. PMID: 28297665
    3. Found a 22 bp deletion and a missense mutation in DDOST. PMID: 22305527
    4. The common SNPs tested in DDOST, PRKCSH and LGALS3 do not seem to be associated with diabetic micro- or macrovascular complications or with type 1 diabetes in Finnish patients. PMID: 20490454
    5. AGER1 provides protection against AGE-induced reactive oxygen species generation via NADPH oxidase and protein kinase C delta. PMID: 19955485

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Congenital disorder of glycosylation 1R (CDG1R)
  • 亞細胞定位:
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    DDOST 48 kDa subunit family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 2728

    OMIM: 602202

    KEGG: hsa:1650

    STRING: 9606.ENSP00000364188

    UniGene: Hs.523145



主站蜘蛛池模板: 日韩av无码一区二区三区| 亚洲精品久久久久午夜福禁果tⅴ| 亚洲第一无码精品立川理惠| 中文字幕无码不卡免费视频| 亚洲综合熟女久久久40p| 人妻熟女久久久久久久| 肥臀熟女一区二区三区| 4hu四虎永久在线观看| 色欲av巨乳无码一区二区 | 国产亚洲日韩欧美另类丝瓜app | 人禽无码视频在线观看| 久久中文字幕无码a片不卡古代 | 精品亚洲国产成人av在线小说| 强奷乱码中文字幕熟女一| 亚洲成在人线av无码| 男女无遮挡猛进猛出免费观看视频 | 伊人久久大香线蕉亚洲| 久久精品网站免费观看| 99久久精品视香蕉蕉| 少妇人妻邻居| 小雪好紧好滑好湿好爽视频| 亚洲国产成人无码av在线播放| 欧美丰满老妇性猛交| 女人张开腿让男桶喷水高潮| 亚洲国产99精品国自产拍| 天天天狠天天碰天天爱| 丰满少妇被猛烈进入无码| 日韩人妻精品一区二区三区视频| 无码无套少妇18p在线直播| 少妇人妻偷人激情视频| 人妻精油按摩bd高清中文字幕| 又湿又黄裸乳漫画无遮挡网站| 国产精品自在拍首页视频 | 热re99久久精品国产99热| 特级av毛片免费观看| 粉嫩虎白女毛片人体| 国产 制服丝袜 动漫在线| 成人影片一区免费观看| 亚洲色在线v中文字幕| 一本大道大臿蕉视频无码| 99热精品久久只有精品|