在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DCHS1 Antibody, HRP conjugated

  • 中文名稱:
    DCHS1兔多克隆抗體, HRP偶聯
  • 貨號:
    CSB-PA850320OB01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) DCHS1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    DCHS1
  • 別名:
    3110041P15Rik antibody; C130033F22Rik antibody; Cadherin-19 antibody; Cadherin-25 antibody; CDH19 antibody; CDH25 antibody; dachsous 1 (Drosophila) antibody; DCHS1 antibody; FIB1 antibody; Fibroblast cadherin-1 antibody; KIAA1773 antibody; OTTMUSP00000015964 antibody; PCD16_HUMAN antibody; PCDH16 antibody; Protein dachsous homolog 1 antibody; Protocadherin-16 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Peptide sequence from Human Protocadherin-16 protein (2964-2981AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    HRP
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Calcium-dependent cell-adhesion protein. Mediates functions in neuroprogenitor cell proliferation and differentiation. In the heart, has a critical role for proper morphogenesis of the mitral valve, acting in the regulation of cell migration involved in valve formation.
  • 基因功能參考文獻:
    1. p.R2330C and p.R2513H were not identified in this cohort. found eight missense variants including six considered deleterious. This includes one novel variant (p.A2464P) and two rare variants (p.R2770Q and p.R2462Q). These variants are predicted to be deleterious with combined annotation-dependent depletion (CADD) scores greater than 25, which are in the same range as p.R2330C (CADD = 28.0) and p.R2513H (CADD = 24.3). PMID: 29224215
    2. The infant was diagnosed with van Maldergem syndrome on the basis of the clinical features and this was subsequently confirmed with genetic analysis, which indicated a homozygous mutation (c.7204G>A p. D2402N ) in the DCHS1 gene PMID: 29505454
    3. Study shows that when key regulators during mammalian cerebral cortical development are disrupted due to DCHS1-FAT4 mutations, functional cerebral asymmetries are stronger. PMID: 25930014
    4. In sum, we establish Dchs1 as a component of the membrane domain surrounding the ciliary base. This suggests a specific role of Dchs1 in PCP-dependent organization of ciliary function and a possible role in lung disease. PMID: 27074579
    5. DCHS1 deficiency in mitral valve prolapse patient mitral valve interstitial cells (MVICs), as well as in Dchs1(+/-) mouse MVICs, result in altered migration and cellular patterning, supporting these processes as aetiological underpinnings for the disease PMID: 26258302
    6. These findings suggest that Fat and Dachsous self-bend due to the loss of Ca(2+)-binding amino acids from specific EC-EC linkers, and can therefore adapt to confined spaces. PMID: 25355906
    7. findings show that mutations in genes encoding the receptor-ligand cadherin pair DCHS1 and FAT4 lead to a recessive syndrome in humans that includes periventricular neuronal heterotopia PMID: 24056717

    顯示更多

    收起更多

  • 相關疾病:
    Van Maldergem syndrome 1 (VMLDS1); Mitral valve prolapse 2 (MVP2)
  • 亞細胞定位:
    Cell membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Expressed in fibroblasts but not in melanocytes or keratinocytes.
  • 數據庫鏈接:

    HGNC: 13681

    OMIM: 601390

    KEGG: hsa:8642

    STRING: 9606.ENSP00000299441

    UniGene: Hs.199850



主站蜘蛛池模板: 人妻体内射精一区二区三四| 欧美亚洲国产第一精品久久| 玩弄人妻少妇老师美妇厨房| 熟女视频一区二区在线观看| 日产精品一区2区卡四卡二卡| 免费无码又爽又刺激一高潮| 3d动漫精品啪啪一区二区中| 久久精品青青草原伊人| 男女无遮挡激情视频| 天天噜噜噜在线视频| av无码电影一区二区三区| 中文字幕日产乱码国内自| 久久亚洲国产成人精品无码区| 中文字幕无码中文字幕有码| 一卡二卡3卡4卡视频免费播放 | 久久人妻av一区二区软件| 狂野欧美性猛xxxx乱大交| 人人狠狠久久亚洲综合88| 亚洲成av人最新无码| 午夜片无码区私人影院| 亚洲欧美日韩久久一区二区| 国产黑色丝袜视频在线观看网红 | 99热成人精品热久久6网站| 天天爽天天爽天天片a| 国产午夜亚洲精品国产成人小说| 成人免费一区二区三区视频| 久久精品人人槡人妻人人玩av | 亚洲精品午夜无码电影网| 无码人妻丰满熟妇奶水区码| 男人扒开添女人下部免费视频| 日本免码va在线看免费| 亚洲v天堂v手机在线| 又大又长粗又爽又黄少妇视频| 中文人妻av久久人妻水密桃| 蜜桃视频在线观看免费网址入口| 人妻少妇精品中文字幕av蜜桃 | 国产白袜脚足j棉袜在线观看| 欧美成人精品福利视频| 无码专区手机在线播放| 亚洲熟妇无码爱v在线观看| 少妇性l交大片毛多|