在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

DCBLD2 Antibody

  • 中文名稱:
    DCBLD2兔多克隆抗體
  • 貨號:
    CSB-PA815855
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA815855(DCBLD2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA815855(DCBLD2 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    DCBLD2
  • 別名:
    1700055P21Rik antibody; AW146002 antibody; CLCP1 antibody; coagulation factor V/VIII-homology domains protein 1 antibody; CUB and LCCL domain-containing protein 2 antibody; CUB antibody; CUB; LCCL and coagulation factor V/VIII-homology domains protein 1 antibody; DCBD2_HUMAN antibody; DCBLD2 antibody; Discoidin antibody; discoidin CUB and LCCL domain containing 2 antibody; Discoidin; CUB and LCCL domain-containing protein 2 antibody; Endothelial and smooth muscle cell-derived neuropilin-like protein antibody; ESDN antibody; LCCL and coagulation factor V/VIII-homology domains protein 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Fusion protein of Human DCBLD2
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:100-1:300
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Dynamic multi-site phosphorylation by Fyn and Abl drives the interaction between CRKL and the novel scaffolding receptors DCBLD1 and DCBLD2. PMID: 29025973
    2. DCBLD2 protein expression profiles were compared between 11 invasive and non-invasive myxofibrosarcomas. Higher DCBLD2 expression was significantly associated with invasive properties of tumor cells. The expression level of DCBLD2 was consistent in different portions of tumor tissues. PMID: 28668639
    3. phosphorylation of DCBLD2 Y750 recruited TRAF6, leading to increased TRAF6 E3 ubiquitin ligase activity and subsequent activation of AKT, thereby enhancing EGFR-driven tumorigenesis PMID: 25061874
    4. ESDN associates with VEGFR-2 and regulates its complex formation with negative regulators of VEGF signaling, protein tyrosine phosphatases PTP1B and TC-PTP, and VE-cadherin. PMID: 24177422
    5. SFK activity was shown to be sufficient, but not required for the interaction between ESDN and the CrkL-SH2 domain PMID: 23770091
    6. ESDN and AP-2g expression is lower in thick melanomas, it is associated with unfavourable histo-pathological parameters (increased vascularity, vascular invasion and mitoses) and correlates with a shorter DFS like for AP-2a. PMID: 23036739
    7. These findings suggest that DCBLD2 could be a potential marker and drug target for treatment of nasal polyposis in Korean asthma patients. PMID: 22261696
    8. Seven SNPs (rs1371687, rs7615856, rs828621, rs828618, rs828616, rs1062196, and rs8833) and one haplotype (DCBLD2-ht1) show associations with susceptibility to AERD. PMID: 22468095
    9. The full-length signal peptides of DCBLD2 is functional and furthermore that the C-domains are sufficient and essential for ER targeting, whereas the N-domains are dispensable. Thus, the N-domains are available for additional functions. PMID: 21183991
    10. our study is the first to identify and validate Endofin, DCBLD2, and KIAA0582 as part of a complex EGF phosphotyrosine signaling network PMID: 17570516
    11. ESDN expression was significantly higher in proliferating, as compared to growth-arrested cells. ESDN overexpression in VSMC led to a decline in growth curves, while ESDN knock down had the opposite effect. PMID: 17697260
    12. These data suggest that down-regulation of DCBLD2, often associated with promoter hypermethylation, is a frequent event that may be related to the development of gastric cancer. PMID: 18314483
    13. ESDN modulates PDGF signaling in VSMCs via regulation of PDGFR beta surface levels. PMID: 19696027

    顯示更多

    收起更多

  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 組織特異性:
    Highly expressed in testis, heart, skeletal muscle and also in cultured vascular smooth muscle cells.
  • 數據庫鏈接:

    HGNC: 24627

    OMIM: 608698

    KEGG: hsa:131566

    STRING: 9606.ENSP00000321573

    UniGene: Hs.203691



主站蜘蛛池模板: 国产a∨精品一区二区三区不卡| 成人做爰视频www网站| 男女一边摸一边做爽爽的免费阅读 | 国产无人区码一码二码三mba| 亚洲va中文字幕| 亚洲欧洲美色一区二区三区| 偷窥村妇洗澡毛毛多| 人妻熟妇乱又伦精品hd| 麻豆高清免费国产一区| 久久久亚洲精品无码| 午夜免费无码福利视频| 漂亮人妻洗澡被公强 日日躁| 又粗又大又硬又长又爽| 亚洲午夜久久久久妓女影院| 国产高潮流白浆视频| 无套中出丰满人妻无码| 寂寞少妇做spa按摩无码| 国产av福利第一精品| 亚洲色大成影网站www永久| 国产男女猛烈无遮挡a片漫画| 最新69国产成人精品视频免费| 国产乱子轮xxx农村| 亚洲中文字幕无码久久2020| 精品成人毛片一区二区| 国产亚洲精品精品国产亚洲综合| 欧美第一黄网免费网站| 99久久免费国产精品| aⅴ亚洲 日韩 色 图网站 播放| 免费精品国产人妻国语| 亚洲另类激情综合偷自拍图片| 成人免费午夜无码视频 | 少妇人妻偷人精品一区二区| 亚洲色成人网站www永久蜜芽| 护士张开腿被奷日出白浆| 亚洲人成人无码www影院| 无码国产精品一区二区免费式芒果| 日本xxxx色视频在线观看| 人妻系列无码一区二区三区| 色翁荡熄又大又硬又粗又动态图| 亚洲国产成人va在线观看天堂| 国产成 人 综合 亚洲|