在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. DBR1 Antibody

DBR1 Antibody

  • 中文名稱：
    DBR1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006529GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    DBR1 antibody; DBR1_HUMAN antibody; Debranching enzyme homolog 1 (S. cerevisiae) antibody; Lariat debranching enzyme antibody; RNA lariat debranching enzyme antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human DBR1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cleaves the 2'-5' phosphodiester linkage at the branch point of lariat intron pre-mRNAs after splicing and converts them into linear molecules that are subsequently degraded. It thereby facilitates ribonucleotide turnover. It may also participate in retrovirus replication via an RNA lariat intermediate in cDNA synthesis.
  • 基因功能參考文獻(xiàn)：
    1. findings support a new view of the early steps in HIV genome replication - they support a model in which lariat formation of viral genomic RNA is important for minus-strand transfer, with DBR1 being required to resolve the lariat to allow reverse transcription to proceed PMID: 28931690
    2. Transcriptomic sequencing confirmed the effect of hDBR1 on RNA splicing, and metabolite profiling supported the observation that neoplasm is triggered by a decrease in hDBR1 expression both in vitro and in vivo. PMID: 28504715
    3. saturation mutagenesis of DBR1 and Gal4 and show that the experimental phenotypes for over 80% of the mutations correlate well with predicted effects of mutations on protein stability and RNA binding affinity. PMID: 26797105
    4. Results of protein-protein interaction between human Dbr1 and factors found in the Intron Large complex identify Xab2 and a novel protein CWF19L1 as specific interactors of DBR1. PMID: 25671812
    5. Inhibition of DBR1 caused a significant reduction in the formation of intermediate and full-length HIV-1 cDNA. PMID: 24672043
    6. Dbr1 protein cleaves the 2'-5' phosphodiester bond of intron lariats, necessary for subsequent intron degradation that follows pre-mRNA splicing. PMID: 1850323

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Lariat debranching enzyme family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 15594

    OMIM: 607024

    KEGG: hsa:51163

    STRING: 9606.ENSP00000260803

    UniGene: Hs.477700



主站蜘蛛池模板： 久久久国产99久久国产久一| 免费看又黄又爽又猛的视频软件| 国产性―交―乱―色―情人| 国产成人精品高清在线观看93| 国产精品久久久久aaaa| 精品夜夜澡人妻无码av蜜桃| 国产色播av在线观看| 日韩a人毛片精品无人区乱码| 国产精品视频二区不卡| 亚洲人亚洲精品成人网站| 日韩在线永久免费播放| 夜夜高潮夜夜爽高清视频| 日韩精品一区二区三区色欲av | 狠狠精品久久久无码中文字幕| 国产在线精品欧美日韩电影| 国产精品美女久久久网站| 波多野结衣的av一区二区三区| 97在线成人国产在线视频| 亚洲熟女av乱码在线观看漫画| 亚洲春色在线视频| 久久久久久人妻一区精品| 亚洲成av人片天堂网老年人| 亚洲人成欧美中文字幕| 成人无码www免费视频| 久久夜色撩人精品国产小说| 好爽...又高潮了毛片| 性少妇无码播放| 亚洲gv猛男gv无码男同| 国产av久久久久精东av| 最近日本免费观看高清视频| 色狠狠久久av五月综合| 久久久久国色av免费看图片| 潮喷大喷水系列无码| 精品av无码国产一区二区| 免费看又黄又爽又猛的视频软件| 日韩精品一卡2卡3卡4卡新区视频| 精品国产第一国产综合精品| 樱花草在线社区www韩国| 国产成人av大片在线观看| 一本一道av无码中文字幕﹣百度| 99精品国产99久久久久久97|