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DAZ2 Antibody

  • 中文名稱：
    DAZ2兔多克隆抗體
  • 貨號：
    CSB-PA623785ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA623785ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA623785ESR1HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) DAZ2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    DAZ2
  • 別名：
    DAZ2 antibody; DAZ2_HUMAN antibody; DAZ3 antibody; Deleted in azoospermia 2 antibody; Deleted in azoospermia protein 2 antibody; Deleted in azoospermia protein 3 antibody; MGC126442 antibody; pDP1678 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Deleted in azoospermia protein 2 protein (1-200AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
  • 基因功能參考文獻：
    1. study reported a new type of AZFc deletion (gr/gr-DAZ2-DAZ4-CDY1b) and hypothesis that this new deletion is the result of 2 successive events favored by the unstable structure of AZFc region; also demonstrated that this deletion constitutes a relative high-risk factor for male infertility in Tunisian population PMID: 27457284
    2. There appears to be an asociation of DAZ1/DAZ2 deletion with spermatogenic impairment and male infertility in the South Chinese population. PMID: 23512232
    3. Deletion of DAZ2 and DAZ4 gene copies is associated with male infertility. PMID: 24878370
    4. DAZ gene copy number in severely idiopathic infertile men. Gene deletion of two copies of DAZ (DAZI and 2) was the cause of spermatogenic damage. PMID: 11883873
  • 相關(guān)疾病：
    Spermatogenic failure Y-linked 2 (SPGFY2)
  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
  • 蛋白家族：
    RRM DAZ family
  • 組織特異性：
    Testis specific.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 15964

    OMIM: 400026

    KEGG: hsa:57055

    STRING: 9606.ENSP00000371870

    UniGene: Hs.592257



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