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  4. DAK Antibody

DAK Antibody

  • 中文名稱：
    DAK兔多克隆抗體
  • 貨號(hào)：
    CSB-PA008649
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TKFC
  • 別名：
    ATP dependent dihydroxyacetone kinase antibody; Bifunctional ATP dependent dihydroxyacetone kinase/FAD AMP lyase (cyclizing) antibody; DAK antibody; DHA kinase antibody; Dha kinase/FMN cyclase antibody; DHAK_HUMAN antibody; Dihydroxyacetone kinase antibody; Dihydroxyacetone kinase 2 antibody; Dihydroxyacetone kinase 2 homolog (S. cerevisiae) antibody; Dihydroxyacetone kinase 2 homolog (yeast) antibody; FAD AMP lyase (cyclic FMN forming) antibody; FAD AMP lyase (cyclizing) antibody; FAD-AMP lyase (cyclic FMN forming) antibody; FAD-AMP lyase (cyclizing) antibody; FMN cyclase antibody; Glycerone kinase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human DHA Kinase.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes both the phosphorylation of dihydroxyacetone and of glyceraldehyde, and the splitting of ribonucleoside diphosphate-X compounds among which FAD is the best substrate. Represses IFIH1-mediated cellular antiviral response.
  • 基因功能參考文獻(xiàn)：
    1. The peptide fragment (m/z 520.3) of DAK is a promising biomarker to guide timing of antiviral treatment and to avoid liver biopsy in compensated chronic hepatitis B patients. PMID: 24289155
    2. analysis of human triokinase/FMN cyclase reveals that kinase activity requires intact homodimers, but cyclase requires only a truncated, single domain subunit PMID: 24569995
    3. Evidence supports that a single protein sustains both FMN cyclase and ATP-dependent Dha kinase activities, probably in a single active center PMID: 16289032
    4. DAK, the physiological suppressor of cytoplasmic viral RNA sensor MDA5, specifically inhibits MDA5- but not RNA helicase RIG-I-mediated innate antiviral signaling. PMID: 17600090
  • 蛋白家族：
    Dihydroxyacetone kinase (DAK) family
  • 組織特異性：
    Detected in erythrocytes (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 24552

    OMIM: 615844

    KEGG: hsa:26007

    STRING: 9606.ENSP00000378360

    UniGene: Hs.6278



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