在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Ctcfl Antibody

Ctcfl Antibody

  • 中文名稱：
    Ctcfl兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006139LA01MO
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: Ctcfl antibody at 6µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 74, 75 kDa
      Observed band size: 74 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Mus musculus (Mouse) Ctcfl Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Ctcfl
  • 別名：
    Ctcfl antibody; Boris antibody; Transcriptional repressor CTCFL antibody; Brother of the regulator of imprinted sites antibody; CCCTC-binding factor antibody; CTCF paralog antibody; CTCF-like protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mouse, Human
  • 免疫原：
    Recombinant Mouse Transcriptional repressor CTCFL protein (1-636AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，Ctcfl Antibody (CSB-PA006139LA01MO)，的標(biāo)記方式是Non-conjugated。對(duì)于Ctcfl Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA006139LB01MO Ctcfl Antibody, HRP conjugated ELISA
    FITC CSB-PA006139LC01MO Ctcfl Antibody, FITC conjugated
    Biotin CSB-PA006139LD01MO Ctcfl Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites. Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
  • 基因功能參考文獻(xiàn)：
    1. CTCF and BORIS cooperate with additional Testis-specific transcriptional regulators to regulate gene expression in developing male gametes. PMID: 28145452
    2. The TGFB pathway as most affected by embryonic Ctcfl expression. PMID: 26169830
    3. down-regulation of endogenous BORIS by specific shRNAs inhibited both RNA transcription and cell cycle progression. The results altogether suggest a role for BORIS in coordinating S phase events with mitosis. PMID: 22724006
    4. Rb2 coimmunolocalizes with the chromatin insulator CCCTC-binding factor (CTCF) and BORIS in T-antigen-positive but not in T-antigen-negative cells. PMID: 22544282
    5. These findings show that BORIS expression is more widespread than previously believed, and suggest a role for BORIS in nucleolar function. PMID: 21811597
    6. These findings define transcriptional regulation of CST (Gal3st1) expression as a critical role for BORIS in spermatogenesis. PMID: 20231363
    7. CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region PMID: 18632606
    8. DNA damage-induced and ATR/Rfx1-mediated increase of miR-709 expression in exposed testes may be a protective mechanism that effectively decreases a cellular level of BORIS to prevent massive aberrant erasure of DNA methylation after radiation exposure. PMID: 19029807

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    CTCF zinc-finger protein family
  • 組織特異性：
    Testis-specific.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 日韩免费人妻av无码专区蜜桃| 男女性杂交内射妇女bbwxz| 日本一区二区三区免费更新不卡| 国产熟妇另类久久久久久| 欧美日产成人高清视频| 337p日本欧洲亚洲大胆裸体艺术| 久久综合久久美利坚合众国| 四虎亚洲精品无码| 国产精品午夜剧场免费观看| 色天使久久综合网天天| 装睡被陌生人摸出水好爽| 天天看片天天av免费观看 | 影音先锋人妻av中文字幕久久| 中文日产幕无线码6区收藏| 国产人妻精品午夜福利免费| 婷婷国产成人精品视频| 久久五十路丰满熟女中出| 日韩在线看片免费人成视频播放 | 欧美成va视频网站| 国产精品第一区揄拍无码| 久久久亚洲精品一区二区三区浴池| 插插无码视频大全不卡网站 | 国产成人无码精品久久涩吧| 性饥渴的农村熟妇| 99这里只有精品| 精品毛片乱码1区2区3区| 337p日本欧洲亚洲大胆精筑| 国产精品久久久久久久久ktv| 无码少妇一区二区三区芒果| 无码人妻一区二区中文| 日韩在线不卡免费视频一区| 少妇厨房愉情理9仑片视频| 强制高潮18xxxx按摩| 日韩v亚洲v欧美v精品综合| 激情五月综合色婷婷一区二区| 国产亚洲精品久久久久小| 精品一区二区成人精品| 免费无码又爽又刺激网站| 人与禽交av在线播放| 中文字幕 欧美精品 第1页| 男女下面进入的视频免费午夜|