在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Ctcfl Antibody

Ctcfl Antibody

  • 中文名稱：
    Ctcfl兔多克隆抗體
  • 貨號(hào)：
    CSB-PA006139LA01MO
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: Ctcfl antibody at 6µg/ml + Hela whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 74, 75 kDa
      Observed band size: 74 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Mus musculus (Mouse) Ctcfl Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Ctcfl
  • 別名：
    Ctcfl antibody; Boris antibody; Transcriptional repressor CTCFL antibody; Brother of the regulator of imprinted sites antibody; CCCTC-binding factor antibody; CTCF paralog antibody; CTCF-like protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mouse, Human
  • 免疫原：
    Recombinant Mouse Transcriptional repressor CTCFL protein (1-636AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，Ctcfl Antibody (CSB-PA006139LA01MO)，的標(biāo)記方式是Non-conjugated。對(duì)于Ctcfl Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA006139LB01MO Ctcfl Antibody, HRP conjugated ELISA
    FITC CSB-PA006139LC01MO Ctcfl Antibody, FITC conjugated
    Biotin CSB-PA006139LD01MO Ctcfl Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites. Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
  • 基因功能參考文獻(xiàn)：
    1. CTCF and BORIS cooperate with additional Testis-specific transcriptional regulators to regulate gene expression in developing male gametes. PMID: 28145452
    2. The TGFB pathway as most affected by embryonic Ctcfl expression. PMID: 26169830
    3. down-regulation of endogenous BORIS by specific shRNAs inhibited both RNA transcription and cell cycle progression. The results altogether suggest a role for BORIS in coordinating S phase events with mitosis. PMID: 22724006
    4. Rb2 coimmunolocalizes with the chromatin insulator CCCTC-binding factor (CTCF) and BORIS in T-antigen-positive but not in T-antigen-negative cells. PMID: 22544282
    5. These findings show that BORIS expression is more widespread than previously believed, and suggest a role for BORIS in nucleolar function. PMID: 21811597
    6. These findings define transcriptional regulation of CST (Gal3st1) expression as a critical role for BORIS in spermatogenesis. PMID: 20231363
    7. CTCFL/BORIS is a methylation-independent DNA-binding protein that preferentially binds to the paternal H19 differentially methylated region PMID: 18632606
    8. DNA damage-induced and ATR/Rfx1-mediated increase of miR-709 expression in exposed testes may be a protective mechanism that effectively decreases a cellular level of BORIS to prevent massive aberrant erasure of DNA methylation after radiation exposure. PMID: 19029807

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    CTCF zinc-finger protein family
  • 組織特異性：
    Testis-specific.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产婷婷丁香五月缴情成人网 | 又大又粗又爽18禁免费看| 最新网站亚洲人成无码| 国内精品视频一区二区八戒| 把腿张开老子臊烂你多p视频| 国外亚洲成av人片在线观看| 国产高清在线精品一区| 欧美大片va欧美在线播放| 日本亚洲欧洲另类图片| av无码久久久久不卡网站下载| 国产内射老熟女aaaa| 国产中老年妇女精品| 国产精品嫩草影院久久| 精品四虎国产在免费观看| 国产亚洲精品久久久久久老妇小说| 国产乱xxxxx97国语对白| 国产精品人人妻人人爽| 精品久久久久久中文墓无码| 激情av无码后入| 中文字幕乱码亚洲无线三区| 亚洲精品成人无码中文毛片| 无码国产玉足脚交极品网站| 国产成人精品无码a区在线观看| 69精品丰满人妻无码视频a片| 亚洲色欲www综合网| 无码精品久久久天天影视| 国产人妻久久精品二区三区老狼 | 揉捏奶头高潮呻吟视频| 爆乳护士一区二区三区在线播放| 五月综合激情婷婷六月色窝| 日韩成人无码中文字幕| 久久精品免视看国产成人| 亚洲色无码中文字幕手机在线| 亚洲一区二区三区影院| 99国产精品久久久蜜芽| 国产亚洲精品岁国产微拍精品| 国产熟妇乱xxxxx大屁股网| 亚洲久悠悠色悠在线播放| 亚洲精品无码你懂的| 少妇愉情理伦片bd| 国产精品毛片a∨一区二区三区|