在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Cleaved-EFNA2 (N188) Antibody

  • 中文名稱:
    Cleaved-EFNA2 (N188)兔多克隆抗體
  • 貨號:
    CSB-PA000043
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of 293 cells using Cleaved-Ephrin-A2 (N188) Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    EFNA 2 antibody; efna2 antibody; EFNA2_HUMAN antibody; ELF1 antibody; Eph related receptor tyrosine kinase ligand 6 antibody; EPH-related receptor tyrosine kinase ligand 6 antibody; Ephrin-A2 antibody; EphrinA2 antibody; EPLG6 antibody; HEK7 L antibody; HEK7 ligand antibody; HEK7-L antibody; HEK7L antibody; LERK 6 antibody; LERK-6 antibody; LERK6 antibody; Ligand of eph related kinase 6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse
  • 免疫原:
    Synthesized peptide derived from the C-terminal region of Human Ephrin-A2.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. With the EPHA2 receptor may play a role in bone remodeling through regulation of osteoclastogenesis and osteoblastogenesis.
  • 基因功能參考文獻:
    1. Ephrin-A2 expression was correlated with Ki-67 expression in PCa patients, both at the gene scale and protein level. Our data indicate that Ephrin-A2 is a potential diagnostic and prognostic biomarker and a promising molecular therapeutic target to attenuate prostate cancer progression PMID: 26561474
    2. these studies suggested that Kaposi's sarcoma-associated herpesvirus utilizes CIB1 as one of the key molecule(s) to coordinate and sustain the EphA2 mediated signaling involved in its entry PMID: 24550731
    3. High EphA2 receptor expression in colorectal cancer was associated with a worse outcome in patients treated with cetuximab-based therapy PMID: 24050852
    4. Implicate EphA2 as a novel proinflammatory mediator and potential regulator of atherosclerotic plaque development. PMID: 22247258
    5. Optic nerve section in adult rat differentially regulates the expression of ephrin-A2 in the superior colliculus(SC).At 1 month, levels were upregulated across the contralateral SC giving rise to an increasing rostro-caudal gradient. PMID: 11860487
    6. Different forms of Elf-1 are the products of posttranslational modifications that determine its subcellular localization, activity, and metabolic degradation. PMID: 11884456
    7. Abnormal posttranslational mechanisms of the Elf-1 protein result in defective expression of the functional 98-kDa form of Elf-1, and consequently, the transcriptional defect of TCR zeta-chain in patients with systemic lupus erythematosus. PMID: 12421992
    8. There is a significant loss of ELF-1 and reduced Smad4 expression in gastrointestinal neoplasms. PMID: 16158060
    9. Elf-1 represents the first transcription factor identified to be involved in the transcriptional regulation of Fc receptor gamma PMID: 17878388

    顯示更多

    收起更多

  • 亞細胞定位:
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族:
    Ephrin family
  • 數據庫鏈接:

    HGNC: 3222

    OMIM: 602756

    KEGG: hsa:1943

    STRING: 9606.ENSP00000215368

    UniGene: Hs.741510



主站蜘蛛池模板: 国产精品美女久久久| 日日干夜夜干| 中文www新版资源在线| 国产亚洲精品久久久美女18黄| 亚洲色自偷自拍另类小说| 亚洲最新无码成av人| 久久青草成人综合网站| 亚洲欧洲日本综合aⅴ在线| 夜夜高潮夜夜爽夜夜爱爱| 亚洲成av人无码综合在线观看 | 熟女人妻av完整一区二区三区| 熟女肥臀白浆大屁股一区二区 | 成人a大片在线观看| 无码人妻斩一区二区三区| 亚洲成a人v欧美综合天堂| 欧美老妇大p毛茸茸| 婷婷五月婷婷五月| 无翼乌工口全彩肉肉无遮挡18| 强行征服邻居人妻淑敏| 欧美无遮挡很黄裸交视频| 欧美刺激性大交| 亚洲精品久久久无码av片软件| 久久精品亚洲精品国产色婷| 国产精品69人妻无码久久| 国产下药迷倒白嫩美女网站| 精品一区二区久久久久久久网站| 老司机亚洲精品影院| 狠狠综合亚洲综合亚洲色| 久久人妻xunleige无码| 熟妇高潮一区二区三区| 亚洲狠狠婷婷综合久久| 手机在线看片| 久久久久国色av免费看图片| 久久精品中文字幕第一页| 亚洲a无码综合a国产av中文| 丰满少妇被猛烈进入高清播放| 在线 无码 中文字幕 强 乱| 丰满又黄又爽少妇毛片 | 国产亚洲欧美日韩在线观看一区| 国产精品一区在线观看你懂的 | 久久精品一本到东京热|