在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Cleaved-C1S (R437) Antibody

Cleaved-C1S (R437) Antibody

  • 中文名稱：
    Cleaved-C1S (R437)兔多克隆抗體
  • 貨號：
    CSB-PA000017
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HeLa cells using Cleaved-C1s HC (R437) Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Basic proline rich peptide IB 1 antibody; C1 esterase antibody; C1S antibody; C1S_HUMAN antibody; Complement C1s subcomponent antibody; Complement C1s subcomponent heavy chain antibody; Complement C1s subcomponent light chain antibody; Complement component 1 s subcomponent antibody; Complement component 1 subcomponent s antibody; FLJ44757 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human C1s HC.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    C1s B chain is a serine protease that combines with C1q and C1r to form C1, the first component of the classical pathway of the complement system. C1r activates C1s so that it can, in turn, activate C2 and C4.
  • 基因功能參考文獻：
    1. TNT003, an inhibitor of the serine protease C1s, prevents complement activation induced by cold agglutinins. PMID: 24695853
    2. Data indicate that complement C1s mRNA level was low in ICR-derived glomerulonephritis (ICGN) mice liver as compared with age-matched ICR mice. PMID: 23989031
    3. A molecular switch governs the interaction between the human complement protease C1s and its substrate, complement C4. PMID: 23592783
    4. Four positively charged amino acids on the serine protease domain appear to form a catalytic exosite that is required for efficient cleavage of C4 in the classical pathway of complement. PMID: 22855709
    5. Detailed mapping of post-translational modifications and insights into the C1r/C1s binding sites. PMID: 20008834
    6. Interaction with the prime side residues at the cleavage point in C1s enhances the affinity of the enzyme for complement 2 and complement 4 substrates; these prime subsite residues mediate positive cooperativity in the cleavage of the substrate. PMID: 14674770
    7. full specificity of the enzyme using a randomized phage display library PMID: 16169853
    8. There are splice variants of C1s mRNA transcripts in normal human cells PMID: 18062908

    顯示更多

    收起更多

  • 相關疾?。?/div>
    Complement component C1s deficiency (C1SD); Ehlers-Danlos syndrome, periodontal type, 2 (EDSPD2)
  • 蛋白家族：
    Peptidase S1 family
  • 數據庫鏈接：

    HGNC: 1247

    OMIM: 120580

    KEGG: hsa:716

    STRING: 9606.ENSP00000328173

    UniGene: Hs.458355



主站蜘蛛池模板： 久久国产人妻一区二区免费| 精产国品一二三产区蘑菇视频| 人妻少妇精品无码专区动漫| 日本va欧美va欧美va精品| 国产a v高清一区二区三区| 高清av熟女一区| 亚洲全部无码中文字幕| 99国产精品久久99久久久| 天天噜噜噜在线视频| 久久久久久国产精品美女| 免费午夜福利不卡片在线| 国产成人无码a区视频在线观看| 无码日韩人妻精品久久蜜桃| 日本免费视频| 国产美女自卫慰水免费视频| 亚洲一区在线日韩在线尤物| 男女下面一进一出无遮挡| 日本人妻丰满熟妇久久久久久| 国产精品乱码人妻一区二区三区| 无人区码一码二码三码区别新月| 少妇精品偷拍高潮少妇小说| 国产精品 欧美 亚洲 制服| 国模冰莲极品自慰人体| 国产xxxx视频在线| 日本一区二区三区不卡免费| 成 人影片 aⅴ毛片免费观看| 草草地址线路①屁屁影院成人| 亚洲五月综合缴情在线| av无码国产精品麻豆| 国产内射一区亚洲| 九九热爱视频精品视频| 国产男女无遮挡猛进猛出 | 免费看国产成年无码av| 少妇精品视频无码专区| 成人做受黄大片| 国产人成无码视频在线| 狠狠色色综合站| 99久久亚洲精品日本无码| 国产肥熟女视频一区二区三区| 亚洲国产欧美一区二区好看电影| 色哟哟免费视频播放网站|