在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CYC1 Antibody

CYC1 Antibody

  • 中文名稱：
    CYC1兔多克隆抗體
  • 貨號：
    CSB-PA580388
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from HepG2 cells, using CYC1 antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CYC1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from internal of Human CYC1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c. Cytochrome c1 is a catalytic core subunit containing a c-type heme. It transfers electrons from the [2Fe-2S] iron-sulfur cluster of the Rieske protein to cytochrome c.
  • 基因功能參考文獻：
    1. these results indicate that CYC1 plays important roles in cell proliferation and comedo necrosis through the elevated oxidative phosphorylation activity in human ductal carcinoma in situ PMID: 28394473
    2. results indicate that miR-661 plays a tumor suppressor role in OS mediated by the downregulation of CYC1, suggesting a potential mechanism underlying cell death resistance in Osteosarcoma. PMID: 28391262
    3. CYC1 promoted tumor metastasis via suppressing activation of AMPK and contributed to tumor growth via facilitating production of ATP. PMID: 27239088
    4. FASL, granzyme B, and cytochrome c blood expression reflects breast cancer progression and response to therapy. (Review) PMID: 27117663
    5. our results provide evidence that CYC1 plays an important role in OS tumorigenesis, and modulation of CYC1 may be an effective strategy to potentiate OS to apoptotic induction by TRAIL. PMID: 25562155
    6. Mutations in CYC1 cause insulin-responsive hyperglycemia. PMID: 23910460
    7. HeLa cells expressing non-cleavable cytochrome c1 maintain mitochondrial morphology and functions. PMID: 21577235
    8. Decreased electron Transport Complex IV activity is associated with ulcerative colitis. PMID: 20440543
    9. Addition of H202 to tendon fibroblasts in vitro resulted in oxidative stress-induced apoptosis and the release of CYC1. PMID: 12788227
    10. the Ca(2+) spike, mitochondrial Bcl-2 presensitization, and subsequent Delta psi(m) transition, Bax translocation, and ROS generation are important upstream signals for cytochrome c release upon stimulation by a Bcl-2 inhibitor. PMID: 14966123
    11. Sensitivity of Cyt c detection in -linked immunosorbent assay is reduced in the presence of serum leucine-rich alpha-2-glycoprotein-1. PMID: 16699948

    顯示更多

    收起更多

  • 相關疾病：
    Mitochondrial complex III deficiency, nuclear 6 (MC3DN6)
  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 蛋白家族：
    Cytochrome c family
  • 數據庫鏈接：

    HGNC: 2579

    OMIM: 123980

    KEGG: hsa:1537

    STRING: 9606.ENSP00000317159

    UniGene: Hs.289271



主站蜘蛛池模板： 亚洲国产成人一区二区精品区| 欧美日韩亚洲中文字幕一区二区三区 | 无码人妻一区二区三区免费| 亚洲伊人久久综合成人| 天天天天噜在线视频| 无码人妻精品一区二区三区久久| 亚欧成人无码av在线播放| 亚洲一区二区三区四区| 午夜福利视频| 狂野av人人澡人人添| 国产麻豆精品精东影业av网站| 亚洲综合区图片小说区| 搡老岳熟女国产熟妇| 亚洲精品无码mv在线观看| 日本19禁啪啪吃奶大尺度| 国产亚洲欧美精品永久| 亚洲成av人片在线观看| 自拍区小说区图片区亚洲 | 综合色区国产亚洲另类| 精品久久久久久久中文字幕| 欧美日韩欧美| 欧美老妇bbbwwbbbww| 少妇被又大又粗猛烈进出视频| 成人18禁深夜福利网站app免费| 东京热无码av一区二区| 国产精品久久久久蜜臀| 婷婷丁香五月天综合东京热| 人人妻人人澡av天堂香蕉| 9l国产精品久久久久尤物| 毛片完整版的免费观看| 国产精品人妻熟女男人的天堂| 国产白嫩美女在线观看| 9九色桋品熟女内射| 天天摸天天摸天天天天看| 欧美真人性做爰一二区| 国产成人无码aⅴ片在线观看| 免费人成网站在线观看欧美| 国产亚洲精品久久一区二区 | 亚洲熟女一区二区三区| 亚欧欧美人成视频在线| 西西人体www44rt大胆高清|