在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CXCL6 Antibody

  • 中文名稱:
    CXCL6兔多克隆抗體
  • 貨號:
    CSB-PA06169A0Rb
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA06169A0Rb at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA06169A0Rb at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CXCL6 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    C X C motif chemokine 6 antibody; Chemokine (C X C motif) ligand 6 antibody; Chemokine alpha 3 antibody; CKA 3 antibody; CKA-3 antibody; CKA3 antibody; CXCL 6 antibody; CXCL6 antibody; CXCL6_HUMAN antibody; GCP 2 antibody; GCP-2 antibody; Granulocyte chemotactic protein 2 antibody; N-processed variant 3 antibody; SCYB6 antibody; Small inducible cytokine B6 antibody; Small inducible cytokine subfamily B (Cys X Cys) member 6 antibody; Small inducible cytokine subfamily B (Cys X Cys) member b antibody; Small-inducible cytokine B6 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human C-X-C motif chemokine 6 protein (38-114AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,CXCL6 Antibody (CSB-PA06169A0Rb),的標記方式是Non-conjugated。對于CXCL6 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA06169B0Rb CXCL6 Antibody, HRP conjugated ELISA
    FITC CSB-PA06169C0Rb CXCL6 Antibody, FITC conjugated
    Biotin CSB-PA06169D0Rb CXCL6 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).
  • 基因功能參考文獻:
    1. CXCL6 could reduce the expression of miR-515-5p in NSCLC cells; MiR-515-5p acted as a tumor suppressor by targeting CXCL6 in non-small cell lung cancer cell cells. PMID: 29136957
    2. Study has provided the first report of fibroblast-derived CXCL12 enhancement of CXCL6 secretion in colon cancer cells, and of both CXCL12 and CXCL6 co-operatively regulating metastasis through the PI3K/Akt/mTOR signaling pathway. PMID: 28811711
    3. CXCL6 expression is upregulated by Fli1 deficiency in fibroblasts and endothelial cells, potentially contributing to the development of fibrosis and vasculopathy in the skin, lung, and heart of systemic sclerosis. PMID: 28507181
    4. CXCL6 level is high in the serum of chronic hepatitis B patients.CXCL6 promotes human hepatocyte proliferation through the CXCR1-NFkappaB pathway and inhibits collagen I secretion by hepatic stellate cells. PMID: 27032929
    5. The role of PITX2 in glaucoma may be mediated partly by regulating the expression of CXCL6 and BBS5 and thus affecting immune functions and intraocular pressure. PMID: 27520585
    6. The neutrophil-recruiting chemokine GCP-2/CXCL6 is expressed in cystic fibrosis airways and retains its functional properties after binding to extracellular DNA. PMID: 25993443
    7. HIF-1alpha promotes HCC progression and metastasis by upregulating CXCL6 transcription in HCC cells. PMID: 25323032
    8. Expression of the CXCL8, CXCL6 and CXCL1 genes are under the primary control of 1,25-dihydroxyvitamin D3 and its receptor. PMID: 24250750
    9. Data suggest that expression of CXCL6 in trophoblasts is up-regulated during pregnancy development/placentation; CXCL6 expression inhibits trophoblast cell migration and invasion by down-regulating activity of MMP2 (matrix metalloproteinase 2). PMID: 23814098
    10. Overexpression of GCP-2 in mesenchymal stem cells has the potential to enhance their angiogenic and survival properties. PMID: 22886775
    11. Studies show that functional blocking of GCP-2 inhibits tumor growth and metastases. PMID: 21236563
    12. The aim of this study was to investigate the role of the transcription factors, AP-1 and NF-kappaB, in IL-6 and CXCL8 regulation in Jurkat T-cells. PMID: 20507572
    13. The level of expression of granulocyte chemotactic protein 2 correlates with the severity of periodontitis and appears to act as a yet unrecognized functional adjunct to interleukin-8 in pathological gingival tissues. PMID: 18842116
    14. results suggest that granulocyte chemotactic protein-2 is an additional ELR(+)-CXC chemokine expressed in endometrial stromal cells PMID: 12524079
    15. induction in mesenchymal cells by interleukin-1beta and down-regulation by interferon-gamma PMID: 12533683
    16. Neutrophil recruitment to inflammatory sites is mediated by two related receptors: CXCR1 and CXCR2. Both receptors share two ligands, interleukin-8 (CXCL8) and GCP-2 (CXCL6). PMID: 12628493
    17. expression in inflamed intestinal tissue in Crohn's disease PMID: 15214047
    18. production of GCP-2 by endothelial cells within the tumor can contribute to tumor development through neovascularization due to endothelial cell chemotaxis and to tumor cell invasion and metastasis PMID: 15652347
    19. LDL lipoprotein subunit L5 induces human umbilical vein endothelial cells (HUVEC) to express CXCL6. PMID: 17022986
    20. These findings indicate that the equilibrium between angiostatic and angiogenic factors during inflammation and tumor progression is rather complex and differs depending on the chemokine, cell type, and stimulus. PMID: 17827342
    21. These observations suggest a role for CXCL6 in the innate immune response to microbial invasion of the amniotic cavity. PMID: 18782286
    22. Report gonadotropin-releasing hormone-regulated CXCL6 expression in human placentation. PMID: 19369450

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Intercrine alpha (chemokine CxC) family
  • 數據庫鏈接:

    HGNC: 10643

    OMIM: 138965

    KEGG: hsa:6372

    STRING: 9606.ENSP00000226317

    UniGene: Hs.164021



主站蜘蛛池模板: 久久不见久久见免费视频6无删减 丰满日韩放荡少妇无码视频 | 亚洲韩国日本高清一区| 13小箩利洗澡无码视频网站| 国产成人8x视频网站入口| 丰满人妻熟妇乱又伦精品软件| 日韩中文高清在线专区| 丰满人妻被黑人中出849| 无码一区二区三区久久精品| 无码区国产区在线播放| 人人模人人爽人人喊久久| 亚洲综合久久成人a片红豆| 香蕉视频在线精品视频| 免费人成在线观看视频播放| 98色婷婷在线| 精品免费国偷自产在线视频| 影音先锋中文字幕人妻| 国产成人精品男人的天堂| 中文无码精品a∨在线观看| 欧美成人无码a区视频在线观看| 欧美老熟妇乱子伦视频| 日韩在线一区二区三区免费视频| 137日本免费肉体摄影| 人人人妻人人人妻人人人| 国产最新进精品视频| 亚洲精品无码av中文字幕电影网站| 老湿机香蕉久久久久久| 国产人妻精品一区二区三区不卡 | 精品免费国产一区二区三区四区| 精品无码久久久久久国产| 国产成人亚洲日韩欧美| 柠檬福利第一导航在线| 亚洲免费人成在线视频观看| 日本熟妇色高清免费视频| 国产在线98福利播放视频| 色窝窝无码一区二区三区成人网站| 亚洲国产欧美在线成人| 乱色国内精品视频在线| 无码人妻精品一区二区蜜桃色欲| 国产精品亚洲一区二区三区| 久久国产欧美成人av| 亚洲人成色77777|