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CWC27 Antibody

  • 中文名稱：
    CWC27兔多克隆抗體
  • 貨號：
    CSB-PA972891
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA972891(CWC27 Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human liver cancer tissue, Human normal colon tissue, human placenta tissue, Primary antibody: CSB-PA972891(CWC27 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Antigen NY CO10 antibody; Antigen NY-CO-10 antibody; CWC27 antibody; CWC27 spliceosome associated protein homolog (S. cerevisiae) antibody; CWC27 spliceosome associated protein homolog S cerevisiae antibody; CWC27_HUMAN antibody; NY CO 10 antibody; NY-CO-10 antibody; peptidyl prolyl cis trans isomerase CWC27 homolog antibody; Peptidyl prolyl cis trans isomerase SDCCAG10 antibody; Peptidyl-prolyl cis-trans isomerase CWC27 homolog antibody; PPIase CWC27 antibody; PPIase SDCCAG10 antibody; SDCCAG10 antibody; Serologically defined colon cancer antigen 10 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthetic peptide of Human CWC27
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity.
  • 基因功能參考文獻：
    1. CWC27 overexpression is associated with Bladder Cancer. PMID: 27206850
    2. By whole-exome sequencing, recessive protein-truncating mutations in CWC27 were found in seven unrelated families that show a range of clinical phenotypes, including retinal degeneration, brachydactyly, craniofacial abnormalities, short stature, and neurologic defects. PMID: 28285769
    3. The crystal structure of a relatively protease-resistant N-terminal fragment of human Cwc27 containing the cyclophilin-type peptidyl-prolyl cis-trans isomerase domain was determined at 2.0 A resolution. PMID: 25478830
  • 相關疾病：
    Retinitis pigmentosa with or without skeletal anomalies (RPSKA)
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Cyclophilin-type PPIase family
  • 數據庫鏈接：

    HGNC: 10664

    OMIM: 250410

    KEGG: hsa:10283

    STRING: 9606.ENSP00000370460

    UniGene: Hs.371372



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