在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CTSE Antibody

CTSE Antibody

  • 中文名稱：
    CTSE兔多克隆抗體
  • 貨號(hào)：
    CSB-PA237699
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA237699(CTSE Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA237699(CTSE Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA237699(CTSE Antibody) at dilution 1/525 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    CTSE
  • 別名：
    CATE antibody; CATE_HUMAN antibody; Cathepsin E antibody; Cathepsin E form II antibody; CTSE antibody; Erythrocyte membrane aspartic proteinase antibody; Slow moving proteinase antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human CTSE
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:100-1:300
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May have a role in immune function. Probably involved in the processing of antigenic peptides during MHC class II-mediated antigen presentation. May play a role in activation-induced lymphocyte depletion in the thymus, and in neuronal degeneration and glial cell activation in the brain.
  • 基因功能參考文獻(xiàn)：
    1. Cathepsin E, mitochondrial fission, and caspase activation/apoptosis are linked in the pathogenesis of pulmonary emphysema. PMID: 25239563
    2. High Expression of Cathepsin E is associated with Tissues but Not Blood of Patients with Barrett's Esophagus and Adenocarcinoma. PMID: 25348778
    3. Decreased activity of cathepsin E produced by decidual macrophages might be responsible for the induction of miscarriages in some recurrent miscarriage patients. PMID: 24464956
    4. data demonstrate that CatE contributes to normal growth and development of mammary glands through proper trafficking and secretion of Wnt5a PMID: 24242330
    5. CTSE is a marker of both gastric differentiation and signet-ring cell carcinoma, which should shed light on the mechanism of gastric tumorigenesis. PMID: 23451082
    6. Cath E activity is useful as a potential molecular target for Pancreatic ductal adenocarcinoma and early detection imaging. PMID: 22068166
    7. A comparative structure model of splice variant 2 was computed based on its alignment to the known structure of cathepsin E intermediate (Protein Data Bank code 1TZS) and used to rationalize its conformational properties and loss of activity. PMID: 22718633
    8. Emerging roles of cathepsin E in immune system cells and skin keratinocytes, and in host defense against cancer cells. PMID: 21664991
    9. Cath E selectivity was established by having -Leu**Pro- residues at the scissile peptide bond. PMID: 20600629
    10. These results suggest the possible involvement of cathepsin E in disruption of the structural and functional integrity of alpha 2-macroglobulin in the endolysosome system. PMID: 12631277
    11. Reduced expression of cathepsin E is observed in erythrocytes of humans with atopic dermatitis. PMID: 14769879
    12. crystal structure of an activation intermediate of cathepsin E at 2.35A resolution PMID: 15342244
    13. Both cathepsin E message and protein are found in human dendritic cells, but are absent in monocytes. PMID: 15699105
    14. Three-dimensional structure of cathepsin-E. PMID: 15845357
    15. the human cathepsin E gene is regulated by the constitutive androstane receptor PMID: 17888866
    16. cathepsin E differentially regulates the nature and function of dendritic cells and macrophages PMID: 17947645
    17. cathepsin E plays a substantial role in host defense against tumor cells through TRAIL-dependent apoptosis and/or tumor-associated macrophage-mediated cytotoxicity PMID: 18006832
    18. CatE is important in the processing of tetanus toxin C-fragment in primary human B cells. PMID: 18996084
    19. This study demonstrates the over-expression in CTSE, in particular, and TFF1 in sessile serrated adenomas compared to both hyperplastic polyps and tubular adenomas. PMID: 19172291

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Endosome. Note=The proenzyme is localized to the endoplasmic reticulum and Golgi apparatus, while the mature enzyme is localized to the endosome.
  • 蛋白家族：
    Peptidase A1 family
  • 組織特異性：
    Expressed abundantly in the stomach, the Clara cells of the lung and activated B-lymphocytes, and at lower levels in lymph nodes, skin and spleen. Not expressed in resting B-lymphocytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 2530

    OMIM: 116890

    KEGG: hsa:1510

    STRING: 9606.ENSP00000350911

    UniGene: Hs.644082



主站蜘蛛池模板： 久久久久免费看成人影片| av影音先锋最大资源网| 国产成人亚洲综合图区| 少妇无码av无码专线区大牛影院| 77777亚洲午夜久久多喷| 亚洲国产精品无码久久| 中文字幕人妻无码一夲道| 老妇女性较大毛片| 国产真实夫妇交换视频| 综合图区亚洲另类偷窥| 亚洲国产成人精品无码区在线秒播| www激情内射在线看| 欧美肥臀大屁股magnet| 精品日产一卡2卡三卡4卡在线| 亚洲精品成人区在线观看| 国产suv精品一区| 国产精品99久久不卡| 最新69国产成人精品视频| 永久黄网站色视频免费看| 国产欧美亚洲精品a| 国产一区二区| 亚洲精品国产福利一区二区| 麻豆av字幕无码中文| 国产av影片麻豆精品传媒| 国内少妇高潮嗷嗷叫在线播放| 熟女人妻视频| 波多野结衣爽到高潮大喷| 免费观看黄网站在线播放| 在线看免费无码av天堂的| 狠狠噜天天噜日日噜视频麻豆 | 日韩精品亚洲人成在线观看| 色婷婷综合中文久久一本| 4hu四虎永久在线观看| 国产麻豆精品久久一二三| 亚洲综合无码中文字幕第2页| 狠狠色老熟妇老熟女| 亚洲精品久久久久中文字幕二区 | 97国产精品麻豆性色aⅴ人妻波| av无码动漫一区二区三区精品| 国产成人综合一区人人| 中字乱码视频|