在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CTPS1 Antibody

  • 中文名稱:
    CTPS1兔多克隆抗體
  • 貨號:
    CSB-PA006176GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CTPS1
  • 別名:
    CTPS1 antibody; CTPS antibody; CTP synthase 1 antibody; EC 6.3.4.2 antibody; CTP synthetase 1 antibody; UTP--ammonia ligase 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CTPS
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
  • 基因功能參考文獻:
    1. CTP synthase forms the cytoophidium in human hepatocellular carcinoma. PMID: 29097181
    2. The filament structures elucidate allosteric mechanisms of assembly and regulation that rely on a conserved conformational equilibrium. The findings may provide a mechanism for increasing human CTP synthase activity in response to metabolic state and challenge the assumption that metabolic filaments are generally storage forms of inactive enzymes. PMID: 28459447
    3. Rods and rings (RR) are protein assemblies composed of CTPS1 and IMPDH2. Glutamine deprivation initiates reversible assembly of mammalian rods and rings. PMID: 24477477
    4. results highlight a key and specific role of CTPS1 in the immune system by its capacity to sustain the proliferation of activated lymphocytes during the immune response PMID: 24870241
    5. analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation PMID: 20739275
    6. CTP synthetase is phosphorylated by protein kinase A PMID: 16179339
    7. Data indicate that protein kinase C phosphorylation at Ser(462) stimulates human CTP synthetase 1 activity, whereas phosphorylation at Thr(455) inhibits activity. PMID: 17463002
    8. analysis of phosphorylation and regulation of human CTPS1 in human cells shows that GSK3 is a novel regulator of CTPS activity PMID: 17681942
    9. studies provide novel information on the potential interacting proteins that may regulate CTPS1 function or intracellular localization PMID: 18600551

    顯示更多

    收起更多

  • 相關疾病:
    Immunodeficiency 24 (IMD24)
  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    CTP synthase family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 2519

    OMIM: 123860

    KEGG: hsa:1503

    STRING: 9606.ENSP00000361699

    UniGene: Hs.473087



主站蜘蛛池模板: 色噜噜狠狠色综合av| 奇米在线7777在线精品| 亚洲精品久久久久中文字幕一福利| 久久伊人av综合影院 | 99久久久国产精品无码免费| 性色a∨精品高清在线观看| 狠狠色噜噜狠狠狠888777米奇| 中文在线www天堂网| 免费大片黄在线观看| 东方aⅴ免费观看久久av| 国产超碰人人做人人爽av| 狠狠色噜噜狠狠狠狠五月婷| 精品国产乱码久久久久久鸭王1| 曰本丰满熟妇xxxx性| 激情综合婷婷丁香五月情| 中文字幕在线精品视频| 亚洲精品久久久中文字幕痴女| 一边摸一边做爽的视频17国产| 精品国产一区二区三区久久狼 | 熟妇玩小男视频在线| 99精品免视看| 97精品人人a片免费看| 国产香蕉国产精品偷在线| 亚洲国产激情一区二区三区| 色婷婷亚洲一区二区综合| 国产成人精品无码一区二区| 国产精品沙发系列| 久久99精品久久久久久2021| 撕开奶罩揉吮奶头视频| 久久国产劲爆∧v内射-百度 | 国产精品青青在线观看爽香蕉| 国产强奷在线播放免费| 国产香蕉尹人在线观看视频| 福利姬液液酱喷水| 免费无码成人av在线播| 午夜福利日本一区二区无码| 国产口爆吞精在线视频2020版 | 激情射精爽到偷偷c视频无码| 亚洲永久无码7777kkk| 在线观看的网站| 国产免费爽爽视频在线观看|