在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CTPS1 Antibody

  • 中文名稱:
    CTPS1兔多克隆抗體
  • 貨號:
    CSB-PA006176GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CTPS1
  • 別名:
    CTPS1 antibody; CTPS antibody; CTP synthase 1 antibody; EC 6.3.4.2 antibody; CTP synthetase 1 antibody; UTP--ammonia ligase 1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CTPS
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IF
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    This enzyme is involved in the de novo synthesis of CTP, a precursor of DNA, RNA and phospholipids. Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as a source of nitrogen. This enzyme and its product, CTP, play a crucial role in the proliferation of activated lymphocytes and therefore in immunity.
  • 基因功能參考文獻:
    1. CTP synthase forms the cytoophidium in human hepatocellular carcinoma. PMID: 29097181
    2. The filament structures elucidate allosteric mechanisms of assembly and regulation that rely on a conserved conformational equilibrium. The findings may provide a mechanism for increasing human CTP synthase activity in response to metabolic state and challenge the assumption that metabolic filaments are generally storage forms of inactive enzymes. PMID: 28459447
    3. Rods and rings (RR) are protein assemblies composed of CTPS1 and IMPDH2. Glutamine deprivation initiates reversible assembly of mammalian rods and rings. PMID: 24477477
    4. results highlight a key and specific role of CTPS1 in the immune system by its capacity to sustain the proliferation of activated lymphocytes during the immune response PMID: 24870241
    5. analysis of the kinetic properties of hCTPS1 and hCTPS2, and determination that Ser(68) is a major site of CTPS2 regulation by phosphorylation PMID: 20739275
    6. CTP synthetase is phosphorylated by protein kinase A PMID: 16179339
    7. Data indicate that protein kinase C phosphorylation at Ser(462) stimulates human CTP synthetase 1 activity, whereas phosphorylation at Thr(455) inhibits activity. PMID: 17463002
    8. analysis of phosphorylation and regulation of human CTPS1 in human cells shows that GSK3 is a novel regulator of CTPS activity PMID: 17681942
    9. studies provide novel information on the potential interacting proteins that may regulate CTPS1 function or intracellular localization PMID: 18600551

    顯示更多

    收起更多

  • 相關疾病:
    Immunodeficiency 24 (IMD24)
  • 亞細胞定位:
    Cytoplasm, cytosol.
  • 蛋白家族:
    CTP synthase family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 2519

    OMIM: 123860

    KEGG: hsa:1503

    STRING: 9606.ENSP00000361699

    UniGene: Hs.473087



主站蜘蛛池模板: 无码国产成人午夜电影观看| 欧美巨鞭大战丰满少妇| 青草影院内射中出高潮-百度| 狠狠色噜噜狠狠狠7777米奇| 夜夜爱夜鲁夜鲁很鲁| 中文字幕人妻无码视频| 日韩久久无码免费毛片软件| 亚洲免费综合色在线视频| 天堂资源在线www在线观看| 色婷婷欧美在线播放内射| 韩国精品一区二区三区四区| 日韩综合亚洲色在线影院| 国产手机精品一区二区| 国产精品国产高清国产av | 中文字幕精品一区二区2021年| 欧美一区二区三区啪啪| 人妻丝袜av先锋影音先| 亚洲成在人网站无码天堂| 国产亚洲欧美精品永久| 综合色区亚洲熟妇另类| 青草久久人人97超碰| 日本动漫瀑乳h动漫啪啪免费 | 狠狠色丁香久久婷婷综合蜜芽五月 | 国产又黄又刺激又高潮的网站| 亚洲国产一区二区精品无码| 色吊丝中文字幕| 美女裸体跪姿扒开屁股无内裤 | 久久精品噜噜噜成人av| 国产精品对白交换视频| 午夜福利电影网站鲁片大全| 亚洲自偷自拍另类小说| 少妇性bbb搡bbb爽爽爽欧美| 亚洲人成无码网www电影麻豆| 精品国产一区二区三区av色诱 | 日本成本人片视频免费| 人人妻人人爽日日人人| 用舌头去添高潮无码视频| 日本丰满熟妇bbxbbxhd| 国产 日韩 欧美 视频 制服| 欧美顶级少妇做爰hd| 性色欲情网站iwww|