在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CSNK1G2 Antibody

CSNK1G2 Antibody

  • 中文名稱：
    CSNK1G2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA007366
  • 規(guī)格：
    ￥1090
  • 圖片：
    • Western Blot analysis of HeLa cells using Casein Kinase Iγ2 Polyclonal Antibody
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    Casein kinase 1; gamma 2 antibody; Casein kinase I isoform gamma 2 antibody; Casein kinase I isoform gamma-2 antibody; CK1g2 antibody; CKI gamma 2 antibody; CKI-gamma 2 antibody; CSNK1G 2 antibody; Csnk1g2 antibody; KC1G2_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the N-terminal region of Human Casein Kinase Iγ2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, IF, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    IF 1:200-1:1000
    ELISA 1:10000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Serine/threonine-protein kinase. Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. It can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates COL4A3BP/CERT, MTA1 and SMAD3. Involved in brain development and vesicular trafficking and neurotransmitter releasing from small synaptic vesicles. Regulates fast synaptic transmission mediated by glutamate. SMAD3 phosphorylation promotes its ligand-dependent ubiquitination and subsequent proteasome degradation, thus inhibiting SMAD3-mediated TGF-beta responses. Hyperphosphorylation of the serine-repeat motif of COL4A3BP/CERT leads to its inactivation by dissociation from the Golgi complex, thus down-regulating ER-to-Golgi transport of ceramide and sphingomyelin synthesis. Triggers PER1 proteasomal degradation probably through phosphorylation.
  • 基因功能參考文獻(xiàn)：
    1. MicroRNA-155 regulates casein kinase 1 gamma 2: a potential pathogenetic role in chronic lymphocytic leukemia PMID: 28885613
    2. MTA1s interacts with CKI-gamma2, which can phosphorylate MTA1s in an antiestrogen-dependent manner.Estrogen stimulates CKI-gamma2. CKI-gamma2 phosphorylates and modulates the functions of MTA1s. PMID: 15077195
    3. Data indicate that SNPs rs740423, rs2277737, rs1059684 of CSNK1G2 gene may contribute to familial febrile convulsions in children. PMID: 15300631
    4. Ligand-dependent ubiquitination of Smad3 is regulated by CK1g2, an inhibitor of TGF-beta signaling. PMID: 18794808
    5. These results indicate that CKIgamma2 hyperphosphorylates the serine-repeat motif of CERT, thereby inactivating CERT and down-regulating the synthesis of sphingomyelin. PMID: 19005213

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm, cell cortex. Cytoplasm.
  • 蛋白家族：
    Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
  • 組織特異性：
    Testis.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 2455

    OMIM: 602214

    KEGG: hsa:1455

    STRING: 9606.ENSP00000255641

    UniGene: Hs.651905



主站蜘蛛池模板： 国产最新进精品视频| 国产精品亚洲а∨无码播放麻豆| 亚洲乱码一区二区三区在线观看| 欧美激情一区二区| 综合久久国产九一剧情麻豆 | 无码国产乱人伦偷精品视频| 欧美片内射欧美美美妇| 欧美日韩精品一区二区性色a+v| √天堂8资源中文在线| 樱花草在线社区www| 日韩欧无码一二三区免费不卡| 午夜亚洲国产理论片中文| 一区二区三区内射美女毛片| 国产精品无码久久久久成人影院| 久久综合九色综合欧美就去吻| 久久被窝亚洲精品爽爽爽| 熟女性饥渴一区二区三区| 欧美性猛交xxxx免费看| 日本亚洲欧美高清专区vr专区| 一边摸一边做爽的免费视频日本| 亚洲国产一区二区三区波多野结衣| 无码人妻丰满熟妇区免费| 变态另类牲交乱| 国产成人无码午夜视频在线观看| 国产精品久久久久久爽爽爽| 亚洲伊人久久综合成人| 欧洲国产精品无码专区影院| 欧美亚洲综合在线一区| 网友自拍区视频精品| 亚洲国产一区二区精品无码| 激情内射亚洲一区二区三区| 永久免费无码日韩视频| 久久性色欲av免费精品观看| 舌头伸进去搅动好爽视频| 忍不住的亲子中文字幕| 日本又黄又潮娇喘视频| 精品免费看国产一区二区| 真人作爱免费视频| 久久久久77777人人人人人 | 极品老师腿张开粉嫩小泬| 麻豆国产97在线 | 欧美|