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  4. CSNK1E Antibody

CSNK1E Antibody

  • 中文名稱：
    CSNK1E兔多克隆抗體
  • 貨號：
    CSB-PA907561
  • 規格：
    ￥2024
  • 圖片：
    • Immunohistochemistry analysis of paraffin-embedded human placenta tissue using CKI-ε antibody.
    • Immunofluorescence analysis of HeLa cells, using CKI-ε antibody.
    • Western blot analysis of extracts from LOVO cells, using CKI-ε antibody.
    • Western blot analysis of extracts from HuvEc cells (Lane 2), JK cells (Lane 3) and cos-7 cells (Lane 4), using CKI-ε antiobdy antiobdy. The lane on the left is treated with synthesized peptide.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CSNK1E Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CSNK1E
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human CKI-ε.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
    IHC 1:50-1:100
    IF 1:100-1:500
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. Can phosphorylate a large number of proteins. Participates in Wnt signaling. Phosphorylates DVL1 and DVL2. Central component of the circadian clock. In balance with PP1, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. Controls PER1 and PER2 nuclear transport and degradation. Inhibits cytokine-induced granuloytic differentiation.
  • 基因功能參考文獻：
    1. CKI-epsilon is a potent TDP-43 kinase in vivo and in vitro. PMID: 24105464
  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily
  • 組織特異性：
    Expressed in all tissues examined, including brain, heart, lung, liver, pancreas, kidney, placenta and skeletal muscle. Expressed in monocytes and lymphocytes but not in granulocytes.
  • 數據庫鏈接：

    HGNC: 2453

    OMIM: 600863

    KEGG: hsa:102800317

    STRING: 9606.ENSP00000352929

    UniGene: Hs.474833



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