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CRYAA Antibody, Biotin conjugated

  • 中文名稱:
    CRYAA兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA006007LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CRYAA Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CRYAA
  • 別名:
    Acry 1 antibody; Alpha crystallin A chain antibody; Alpha-crystallin A chain antibody; CRYA 1 antibody; CRYA1 antibody; CRYAA antibody; CRYAA_HUMAN antibody; Crystallin alpha 1 antibody; Crystallin alpha A antibody; Heat shock protein beta 4 antibody; Heat shock protein beta-4 antibody; HSPB 4 antibody; HspB4 antibody; short form antibody; Zonular Central Nuclear Cataract antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Alpha-crystallin A chain protein (98-173AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Contributes to the transparency and refractive index of the lens. In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
  • 基因功能參考文獻:
    1. CRISPR/Cas9-mediated mutation of the alphaA-crystallin gene in rabbits recapitulates phenotypes of congenital cataracts, microphthalmia, obscurity, and early atrophy of the lens, and failed differentiation of lens fibers. PMID: 28475701
  • 相關疾病:
    Cataract 9, multiple types (CTRCT9)
  • 亞細胞定位:
    Cytoplasm. Nucleus. Note=Translocates to the nucleus during heat shock and resides in sub-nuclear structures known as SC35 speckles or nuclear splicing speckles.
  • 蛋白家族:
    Small heat shock protein (HSP20) family
  • 組織特異性:
    Expressed in the eye lens (at protein level).
  • 數據庫鏈接:

    HGNC: 2388

    OMIM: 123580

    KEGG: hsa:102724652

    STRING: 9606.ENSP00000291554

    UniGene: Hs.184085



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