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CRTAC1 Antibody

  • 中文名稱:
    CRTAC1兔多克隆抗體
  • 貨號:
    CSB-PA005997LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Western Blot
      Positive WB detected in: 293 whole cell lysate, A549 whole cell lysate
      All lanes: CRTAC1 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 72, 71, 69 kDa
      Observed band size: 72 kDa
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CRTAC1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CRTAC1
  • 別名:
    68 kDa chondrocyte expressed protein antibody; 68 kDa chondrocyte-expressed protein antibody; Acidic secreted protein in cartilage antibody; ASPIC antibody; ASPIC1 antibody; Cartilage acidic protein 1 antibody; Cartilage acidic protein 1 precursor antibody; CEP 68 antibody; CEP-68 antibody; CEP68 antibody; Chondrocyte expressed protein 68 kDa CEP 68 antibody; CRAC1_HUMAN antibody; CRTAC1 antibody; Protein CRTAC1-B antibody; W307 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Cartilage acidic protein 1 protein (309-661AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,CRTAC1 Antibody (CSB-PA005997LA01HU),的標記方式是Non-conjugated。對于CRTAC1 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA005997LB01HU CRTAC1 Antibody, HRP conjugated ELISA
    FITC CSB-PA005997LC01HU CRTAC1 Antibody, FITC conjugated
    Biotin CSB-PA005997LD01HU CRTAC1 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 基因功能參考文獻:
    1. Confirm the increase of CRTAC1 in cartilage biopsies from OA patients undergoing joint replacement by real-time PCR and immunohistochemistry. Furthermore, we report that proinflammatory cytokines interleukin-1beta and tumor necrosis factor alpha upregulate CRTAC1 expression in primary articular chondrocytes and synovial fibroblasts. PMID: 27415616
    2. It was shown for the first time the propensity of CRTAC1 to form amyloid-like structures, and it was hypothesized that the aggregating property of CRTAC1 may be related to its disease-association. PMID: 27862299
    3. These results provided new insights into the mechanism of cataract development, and demonstrated that CRTAC1 could be a potentially novel target for cataract treatment. PMID: 27855397
    4. CRTAC1 acquired an alternate last exon from the tail-to-tail oriented neighbouring gene in humans resulting in the glycosylated isoform CRTAC1-A which represents a new extracellular matrix molecule of articular cartilage. PMID: 17074475
    5. in bone fracture patients, 12 proteins were related to bone/cartilage metabolism, including: TGF-beta induced protein IG-H(3), cartilage acidic protein 1, procollagen C proteinase enhancer protein and TGF-beta receptor III. PMID: 17602227

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  • 亞細胞定位:
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性:
    Expressed in the interterritorial matrix of articular deep zone cartilage (at protein level). Isoform 1 and isoform 2 are expressed in brain. Isoform 1 is detected in lung and chondrocytes. Detected in cartilage, bone, cultured chondrocytes and lung, and
  • 數據庫鏈接:

    HGNC: 14882

    OMIM: 606276

    KEGG: hsa:55118

    STRING: 9606.ENSP00000359629

    UniGene: Hs.500736



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