在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CPOX Antibody

  • 中文名稱:
    CPOX兔多克隆抗體
  • 貨號:
    CSB-PA005910GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CPOX
  • 別名:
    Coprogen oxidase antibody; COPROPORPHYRIA antibody; Coproporphyrinogen III oxidase antibody; Coproporphyrinogen Oxidase (CPOX) antibody; Coproporphyrinogen-III oxidase antibody; Coproporphyrinogenase antibody; COX antibody; CPO antibody; Cpox antibody; CPX antibody; HEM 6 antibody; Hem-6 antibody; Hem6 antibody; HEM6_HUMAN antibody; mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CPOX
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
  • 基因功能參考文獻:
    1. The monomer form of mutated CPOX did not show any activity and homodimeric enzymes derived from Hereditary coproporphyria (HCP) mutant showed low activity (<20% of the control). PMID: 24078084
    2. Polymorphism of coproporphyrinogen oxidase is associated with genetic susceptibility to the adverse neurobehavioral effects of Hg exposure in children. PMID: 22765978
    3. Deletion of the fifth exon in the CPOX gene is associated with hereditary coproporphyria. PMID: 21231929
    4. CPOX polymorphisms are associated with biological media contamination and apoptosis disorders. PMID: 22288185
    5. competitive action of both uroporphyrinogen decarboxylase and CPO on the same diacetate porphyrinogen substrate provides additional perspectives on the potential existence of abnormal pathways for heme biosynthesis PMID: 21277781
    6. disease-producing mutations in the CPO gene in nine Swedish families with hereditary coproporphyria PMID: 12181641
    7. coproporphyrinogen III oxidase sequence matches many structural features from urate oxidase PMID: 12208494
    8. Modulation of penetrance by the wild-type allele in dominantly inherited erythrohepatic and acute hepatic porphyrias was studied using CPO. PMID: 14669009
    9. All other type of mutations or missense mutations mapped elsewhere throughout the CPO gene, lead to coproporphyrin accumulation and subsequently typical HCP. PMID: 16159891
    10. CPO mutations form the structural basis of hereditary coproporphyria. PMID: 16176984
    11. The Km recognition) and Kcat values for coproporphyrinogen III and IV were determined. PMID: 16258391
    12. His158 of human CPO may have a role in the active site, but none of the conserved histidine residues of human coproporphyrinogen oxidase is essential for catalytic activity. PMID: 17179900
    13. The authors report the association of a novel mutation in the coproporphyrinogen oxidase gene in an Irish pedigree with the devlopment of hereditary coproporphyria PMID: 18557518
    14. Three of the novel missense mutations and one frameshift mutation was detected in coproporphyrinogen III oxidase (CPO) gene in five Italian patients affected by Hereditary Coproporphyria (HCP). PMID: 19267996
    15. biochemical & kinetic properties of CPOX4, the product of a polymorphism of the CPOX gene that modifies effects of mercury on neurobehavioral function; suggests CPOX4 may predispose to impaired heme biosynthesis which is limited further by Hg exposure PMID: 19339664

    顯示更多

    收起更多

  • 相關疾病:
    Hereditary coproporphyria (HCP)
  • 亞細胞定位:
    Mitochondrion intermembrane space.
  • 蛋白家族:
    Aerobic coproporphyrinogen-III oxidase family
  • 數據庫鏈接:

    HGNC: 2321

    OMIM: 121300

    KEGG: hsa:1371

    STRING: 9606.ENSP00000264193

    UniGene: Hs.476982



主站蜘蛛池模板: 成年片色大黄全免费软件到| 久久人人超碰精品caoporen| av第一福利网站| 又粗又大又黄又爽的免费视频| 青青草99久久精品国产综合| 国产人碰人摸人爱免费视频| 77777亚洲午夜久久多人| 国产情侣草莓视频在线| 天天躁夜夜躁狠狠综合2020| 国内精品久久久久影院一蜜桃| 亚洲欧美丝袜精品久久| 无遮挡激情视频国产在线观看| 国产sp调教打屁股视频网站| 影音先锋每日av色资源站| 两个人看的www在线观看| 亚洲精品综合一区二区三区在线| 亚洲中文精品久久久久久| 蜜桃视频无码区在线观看 | 成人午夜高潮a∨猛片| 国产ae86亚洲福利入口| 色琪琪丁香婷婷综合久久| 精品人妻系列无码人妻漫画| 国产偷抇久久精品a片69 | 99久久精品免费看国产| 亚洲日韩中文无码久久| 电影内射视频免费观看| 欧美成 人 网 站 免费| 亚洲爆乳无码精品aaa片蜜桃| 国产亚洲精品a在线| 天天摸天天做天天添欧美| 无码乱码av天堂一区二区| 国产综合精品| 久久精品无码专区免费青青| 亚洲精品成人网站在线观看| 人妻奶水人妻系列| 免费国产黄网在线观看| av中文无码韩国亚洲色偷偷| 无套内谢老熟女| 成人国产片视频在线观看| 国产精品毛片在线完整版sab| 亚洲精品美女久久7777777|