在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CPOX Antibody

  • 中文名稱:
    CPOX兔多克隆抗體
  • 貨號:
    CSB-PA005910GA01HU
  • 規格:
    ¥3,900
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CPOX
  • 別名:
    Coprogen oxidase antibody; COPROPORPHYRIA antibody; Coproporphyrinogen III oxidase antibody; Coproporphyrinogen Oxidase (CPOX) antibody; Coproporphyrinogen-III oxidase antibody; Coproporphyrinogenase antibody; COX antibody; CPO antibody; Cpox antibody; CPX antibody; HEM 6 antibody; Hem-6 antibody; Hem6 antibody; HEM6_HUMAN antibody; mitochondrial antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human CPOX
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
  • 基因功能參考文獻:
    1. The monomer form of mutated CPOX did not show any activity and homodimeric enzymes derived from Hereditary coproporphyria (HCP) mutant showed low activity (<20% of the control). PMID: 24078084
    2. Polymorphism of coproporphyrinogen oxidase is associated with genetic susceptibility to the adverse neurobehavioral effects of Hg exposure in children. PMID: 22765978
    3. Deletion of the fifth exon in the CPOX gene is associated with hereditary coproporphyria. PMID: 21231929
    4. CPOX polymorphisms are associated with biological media contamination and apoptosis disorders. PMID: 22288185
    5. competitive action of both uroporphyrinogen decarboxylase and CPO on the same diacetate porphyrinogen substrate provides additional perspectives on the potential existence of abnormal pathways for heme biosynthesis PMID: 21277781
    6. disease-producing mutations in the CPO gene in nine Swedish families with hereditary coproporphyria PMID: 12181641
    7. coproporphyrinogen III oxidase sequence matches many structural features from urate oxidase PMID: 12208494
    8. Modulation of penetrance by the wild-type allele in dominantly inherited erythrohepatic and acute hepatic porphyrias was studied using CPO. PMID: 14669009
    9. All other type of mutations or missense mutations mapped elsewhere throughout the CPO gene, lead to coproporphyrin accumulation and subsequently typical HCP. PMID: 16159891
    10. CPO mutations form the structural basis of hereditary coproporphyria. PMID: 16176984
    11. The Km recognition) and Kcat values for coproporphyrinogen III and IV were determined. PMID: 16258391
    12. His158 of human CPO may have a role in the active site, but none of the conserved histidine residues of human coproporphyrinogen oxidase is essential for catalytic activity. PMID: 17179900
    13. The authors report the association of a novel mutation in the coproporphyrinogen oxidase gene in an Irish pedigree with the devlopment of hereditary coproporphyria PMID: 18557518
    14. Three of the novel missense mutations and one frameshift mutation was detected in coproporphyrinogen III oxidase (CPO) gene in five Italian patients affected by Hereditary Coproporphyria (HCP). PMID: 19267996
    15. biochemical & kinetic properties of CPOX4, the product of a polymorphism of the CPOX gene that modifies effects of mercury on neurobehavioral function; suggests CPOX4 may predispose to impaired heme biosynthesis which is limited further by Hg exposure PMID: 19339664

    顯示更多

    收起更多

  • 相關疾病:
    Hereditary coproporphyria (HCP)
  • 亞細胞定位:
    Mitochondrion intermembrane space.
  • 蛋白家族:
    Aerobic coproporphyrinogen-III oxidase family
  • 數據庫鏈接:

    HGNC: 2321

    OMIM: 121300

    KEGG: hsa:1371

    STRING: 9606.ENSP00000264193

    UniGene: Hs.476982



主站蜘蛛池模板: 国产一区二区三区乱码| 日韩国产亚洲高清在线久草| 中文字日产乱码免费1~3软件| 亚洲一区在线日韩在线尤物| 中文字幕亚洲码在线观看| 欧美与黑人午夜性猛交久久久| 国产成人亚洲精品| 亚洲精品色播一区二区| 国产成人综合日韩精品无码不卡| 18禁止看的免费污网站| 久久免费的精品国产v∧| 天堂俺去俺来也www色官网| 国产成人美女视频网站| 中文字幕无码家庭乱欲| 久久精品99国产国产精| 伊人亚洲综合影院首页| 亚洲色欲在线播放一区| 亚洲国产精久久久久久久| 四虎影成人精品a片| 女人被狂爆到高潮免费视频| 国产v亚洲v天堂a无码99| 日韩内射美女人妻一区二区三区| 亚洲经典三级| 亚洲精品国产情侣av在线| 精品无码国产自产在线观看水浒传| 日日碰狠狠躁久久躁婷婷| 亚欧无线一线二线三线区别| 欧美人与善在线com| 开心五月激情综合婷婷色| 亚洲日韩精品欧美一区二区一| 任你干视频精品播放| 强 暴 疼 哭 处 女 身子视频| 欧美黑人又粗又大又爽免费| 狠狠亚洲婷婷综合色香五月排名| 国产精成a品人v在线播放| 国产亚洲精品久久yy50| 国产乱子伦精品视频| 在线播放人成视频观看| 色婷婷亚洲一区二区综合| 免费毛片全部不收费的| 真实国产乱子伦视频|