CPA6 Antibody
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中文名稱:CPA6兔多克隆抗體
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貨號:CSB-PA005880GA01HU
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規格:¥3,900
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其他:
產品詳情
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Uniprot No.:
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基因名:CPA6
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別名:CPA6 antibody; CPAHCarboxypeptidase A6 antibody; EC 3.4.17.- antibody
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宿主:Rabbit
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反應種屬:Human,Mouse,Rat
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免疫原:Human CPA6
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免疫原種屬:Homo sapiens (Human)
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抗體亞型:IgG
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純化方式:Antigen Affinity Purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式:Liquid
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應用范圍:ELISA,IHC
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Protocols:
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
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功能:May be involved in the proteolytic inactivation of enkephalins and neurotensin in some brain areas. May convert inactive angiotensin I into the biologically active angiotensin II. Releases a C-terminal amino acid, with preference for large hydrophobic C-terminal amino acids and shows only very weak activity toward small amino acids and histidine.
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基因功能參考文獻:
- Common variants in PRPF31 and CPA6 were associated with worse and better metformin response, respectively. PMID: 29650774
- these mutations in CPA6 are deleterious and provide further evidence for the involvement of CPA6 mutations in the predisposition for several types of epilepsy. PMID: 25875328
- Significantly higher levels of DNA methylation are found in the CPA6 promoter in focal epilepsy and febrile seizure patients. PMID: 24290490
- These results provide further evidence for the involvement of CPA6 mutations in human epilepsy. PMID: 23105115
- CPA6 mutatins are genetically linked to an autosomal recessive familial form of febrile seizures and temporal lobe epilepsy (TLE), and are associated with sporadic TLE cases. PMID: 21922598
- Substrate specificity of human carboxypeptidase A6 PMID: 20855895
- The CPAH gene was interrupted in a patient with DURS carrying a translocation break point in the DURS1 region on chromosome 8q13. PMID: 12454025
- CPA6 may have a role in the regulation of neuropeptides in the extracellular environment within the olfactory bulb and other parts of the brain PMID: 18178555
- Thrombin activation of osteopontin (OPN) (resulting in OPN-R) and its subsequent inactivation by thrombin-activatable carboxypeptidase B (generating OPN-L) occurs locally within inflamed joints in rheumatoid arthritis. PMID: 19790060
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相關疾?。?/div>Epilepsy, familial temporal lobe, 5 (ETL5); Febrile seizures, familial, 11 (FEB11)亞細胞定位:Secreted, extracellular space, extracellular matrix.蛋白家族:Peptidase M14 family組織特異性:Expressed in the hippocampus, nucleus raphe, and cortex.數據庫鏈接:
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