在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

COX10 Antibody

  • 中文名稱:
    COX10兔多克隆抗體
  • 貨號:
    CSB-PA621520ESR1HU
  • 規(guī)格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: COX10 antibody at 5.31μg/ml + Mouse gonadal tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 49, 28 kDa
      Observed band size: 49 kDa
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA621520ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA621520ESR1HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) COX10 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    2410004F01Rik antibody; AU042636 antibody; COX10 antibody; COX10_HUMAN antibody; Cytochrome c oxidase assembly protein antibody; Cytochrome c oxidase subunit X antibody; Heme A farnesyltransferase antibody; Heme O synthase antibody; OTTMUSP00000006085 antibody; Protoheme IX farnesyltransferase; mitochondrial antibody; Protoheme IX farnesyltransferase; mitochondrial precursor antibody; RP23-78H18.1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Protoheme IX farnesyltransferase, mitochondrial protein (1-160AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Converts protoheme IX and farnesyl diphosphate to heme O.
  • 基因功能參考文獻:
    1. On the basis of its pivotal role in regulating cell death upon COX dysfunction, CerS6 might potentially represent a novel target for therapeutic intervention in mitochondrial diseases caused by COX dysfunction. PMID: 25766330
    2. ISCU and COX10 are target genes of miR-210 related to mitochondrial metabolism PMID: 20498629
    3. COX 15 mRNA was significantly more abundant in the cerebral tissue of Alzheimer's disease (AD) patients and COX10 and COX15 SNP were significantly less represented in the patient group, suggesting a possible protective role toward the risk for AD PMID: 19826901
    4. The expression of the AOX, well-tolerated by the cells, compensates for both the growth defect and the pronounced oxidant-sensitivity of COX-deficient human cells. PMID: 20049701
    5. Cytochrome c oxidase is decreased significantly in platelets and hippocampus in Alzheimer patients compared to controls. PMID: 11959398
    6. COX10 has a role in mitochondrial heme A biosynthesis PMID: 12928484
    7. This study report a cytochrome c oxidase (COX)-deficient patient, clinically affected with Leigh-like disease, with a homozygous mutation in the COX10 start codon. PMID: 15455402
    8. Geranylgeranyltransferase inhibitor-2147 (GGTI-2147), an inhibitor of this enzyme prenylation, elicited significant inhibition of glucose-stimulated insulin secretion from INS 832/13 islet cells. PMID: 17192483

    顯示更多

    收起更多

  • 相關疾病:
    Mitochondrial complex IV deficiency (MT-C4D); Leigh syndrome (LS)
  • 亞細胞定位:
    Mitochondrion membrane; Multi-pass membrane protein.
  • 蛋白家族:
    UbiA prenyltransferase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 2260

    OMIM: 220110

    KEGG: hsa:1352

    STRING: 9606.ENSP00000261643

    UniGene: Hs.462278



主站蜘蛛池模板: 老牛精品亚洲成av人片| 欧亚乱熟女一区二区三区在线| 亚洲国产av无码一区二区三区 | 亚洲熟妇无码av在线播放| 狠狠亚洲婷婷综合色香五月排名| 亚洲精品久久久久久久久久久捆绑 | 搡老熟女国产| 国产免费久久久久久无码| 国产欧美另类久久久精品图片| 中文字幕人妻被公上司喝醉506| 国产精品一区二区熟女不卡| 亚洲妇熟xxxx妇色黄| 最新网站亚洲人成无码| 日韩欧美激情兽交| 成人h动漫精品一区二区无码| 亚洲日韩乱码久久久久久| 在线观看国产成人av片| 狠狠噜狠狠狠狠丁香五月| 护士人妻hd中文字幕| 中文字幕日本六区小电影| 97夜夜澡人人爽人人喊a| 国内精品久久久久影院免费| 乱人伦中文无码视频| 欧洲乱码伦视频免费| 久久99国产只有精品| 日本一区二区三区免费播放视频站| 少妇的丰满人妻hd高清| 欧美激情a∨在线视频播放| 欧美性猛交xxxx乱大交丰满| 久久国产免费观看精品3| 精品一区二区三区自拍图片区| 亚洲国产婷婷六月丁香| 日韩在线永久免费播放| 特级毛片全部免费播放| 6699嫩草久久久精品影院| 都市激情 在线 亚洲 国产| 国产少妇高潮在线观看| 欧美一区二区三区红桃小说| 中文字幕乱码中文乱码777 | 初尝黑人巨砲波多野结衣| 伊人久久大香线蕉av一区二区|