COQ5 Antibody

說明書

產品詳情

Uniprot No.：

Q5HYK3
基因名：

COQ5
別名：

COQ52-methoxy-6-polyprenyl-1,4-benzoquinol methylase antibody; mitochondrial antibody; EC 2.1.1.201 antibody; Ubiquinone biosynthesis methyltransferase COQ5 antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human COQ5
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Methyltransferase required for the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2).
基因功能參考文獻：
1. This is the first report of primary CoQ10 deficiency caused by loss of function of COQ5, with delineation of the clinical, laboratory, histological, and molecular features, and insights regarding targeted treatment with CoQ10 supplementation. PMID: 29044765
2. The expression of COQ5 was increased. PMID: 27155576
3. The results that knockdown of the COQ5 gene reduced CoQ10 levels further indicated the critical role of COQ5 in the biosynthesis of CoQ10. PMID: 23354120
亞細胞定位：

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
蛋白家族：

Class I-like SAM-binding methyltransferase superfamily, MenG/UbiE family
組織特異性：

Widely expressed, with highest levels in liver, lung, placenta and skeletal muscle.
數據庫鏈接：

HGNC: 28722

OMIM: 616359

KEGG: hsa:84274

STRING: 9606.ENSP00000288532

UniGene: Hs.17250

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