在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CNTF Antibody

  • 中文名稱:
    CNTF兔多克隆抗體
  • 貨號:
    CSB-PA06039A0Rb
  • 規格:
    ¥440
  • 圖片:
    • Immunofluorescence staining of U251 cells with CSB-PA06039A0Rb at 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
    • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA06039A0Rb at dilution of 1:50
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CNTF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Ciliary neurotrophic factor antibody; CNTF antibody; CNTF_HUMAN antibody; HCNTF antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Ciliary neurotrophic factor protein (4-196AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,CNTF Antibody (CSB-PA06039A0Rb),的標記方式是Non-conjugated。對于CNTF Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA06039B0Rb CNTF Antibody, HRP conjugated ELISA
    FITC CSB-PA06039C0Rb CNTF Antibody, FITC conjugated
    Biotin CSB-PA06039D0Rb CNTF Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.
  • 基因功能參考文獻:
    1. Our findings suggest that CNTF over-expression enhances the protective effects of bone marrow mesenchymal stem cells on retinal pigment epithelium cells, thus indicating subretinal-transplantation of CNTF-bone marrow mesenchymal stem cells may be a promising therapy for blue-light -injured retina PMID: 29564604
    2. Cytokines of the LIF/CNTF family and metabolism PMID: 26817395
    3. High hydrostatic pressure enables almost 100% refolding of recombinant human ciliary neurotrophic factor from inclusion bodies at high concentration. PMID: 28323167
    4. CNTFR-specific mutants of CNTF have been developed that bind to the CNTFRalpha-LIFRbeta-gp130 receptor. PMID: 26187860
    5. Human CNTF expression through lentiviral gene transfer in the rat striatum significantly decreased the levels of neuronal metabolites (N-acetyl-aspartate, N-acetyl-aspartyl-glutamate, and glutamate). PMID: 25833344
    6. the biological effects of CNTF on retinoic acid (RA)-predifferentiated SH-SY5Y neuroblastoma cells and the underlying molecular mechanism of this effect were investigated for the first time PMID: 25118897
    7. R28E mutation in CNTF abrogatesIL-6 receptor-dependent but retains CNTF receptor-dependent signaling via glycoprotein 130/ LIFR. PMID: 24802752
    8. In this review, CNTF plays an important role in neurogenesis and differentiation of neural stem cells. PMID: 23948898
    9. The levels of expression and secretion of BDNF and CTNF of induced cells were assessed using immunocytochemical, Real-Time polymerase chain reaction, and enzyme linked immunosorbent assay (ELISA). PMID: 23944834
    10. CNTF elevated in umbilical cord blood from pre-eclamptic pregnancies PMID: 23654315
    11. CNTF-mediated protection of photoreceptors requires initial activation of the cytokine receptor gp130 in Muller glial cells. PMID: 24191003
    12. Report favourable allelic patterns of ACTN3 and CNTF genes on aerobic performance in athletes. PMID: 23676962
    13. Data indicate that aspirin increased mRNA and protein expression of CNTF in primary mouse and human astrocytes in a dose- and time-dependent manner. PMID: 23653362
    14. we show that the release of CNTF by glial cells is a very powerful stimulus for optic fiber regeneration and retinal ganglion cell survival after optic nerve crush PMID: 23194670
    15. Ciliary neurotrophic factor levels were increased in painful PTT only. PMID: 22337942
    16. Peptide 6c, corresponding to human CNTF amino acid residues 147-150, induces neurogenesis, neuronal activity and proliferation of immature neurons in the dentate gyrus and improvement of spatial reference memory in mice. PMID: 20952820
    17. CNTF's effects on retinal pigment epithelial (RPE) physiology PMID: 21912637
    18. Data show that variants in CNTF were significantly associated with a lower age at onset of the eating disorders. PMID: 20219210
    19. The role played by CNTF in retinal cell differentiation and survival in retinal progenitors, is reported. PMID: 20428961
    20. Ciliary neurotrophic factor, and related (CNTF), ligands targeting the established CNTF receptor alpha, binds to sortilin with high affinity. PMID: 20584990
    21. In women the CNTF polymorphism (odds ratio (OR) = 2.15, 95%CI: 1.27-3.64, p = 0.004) are associated with weight gain. PMID: 19833146
    22. Studies indicate that leptin, CNTF, LIF and IL-6 present similar three-dimensional fold structure, interact with related class-I receptors and activate similar intracellular pathways. PMID: 19751193
    23. A null mutation in this protein was evaluated for a relationship to disease susceptibility and disease severity in patients with multiple sclerosis. PMID: 11857064
    24. Association of a null mutation in the CNTF gene with early onset of multiple sclerosis. PMID: 11890844
    25. Early onset of severe familial amyotrophic lateral sclerosis with a SOD-1 mutation: potential impact of CNTF as a candidate modifier gene. PMID: 11951178
    26. CTNF binds to the IL-6 receptor and has a role in neuroprotection PMID: 12643274
    27. no evidence found to suggest that ciliary neurotrophic factor is involved in the pathogenesis of pelvic endometriosis PMID: 12890930
    28. Constitutive expression of cytokines in brain induces changes in gene expression characteristic of chronic inflammation leading to either temporal weight reduction (CNTF) or severe cachexia (leukemia inhibitory factor). PMID: 14715713
    29. Results do not support an effect of the CNTF null allele on body composition, contrary to previous findings. PMID: 14747836
    30. findings support the hypothesis that CNTF and leptin engage distinct CNS sites and CNTF possesses inflammatory properties distinct from leptin PMID: 15047605
    31. In spite of axokine gene expression in retinal pigment epithelium, no photoreceptor rescue in retinal degeneration mice. PMID: 15180291
    32. myogenic lineage-committed human myoblasts can dedifferentiate at a clonal level; CNTF is a novel regulator of skeletal myoblast dedifferentiation via p44/p42 MAPK pathway PMID: 15843428
    33. CNTF negatively regulates phototransduction, which reduces the photoresponsiveness of rods, resulting in lower electroretinogram amplitudes following light stimulus. PMID: 17192435
    34. Possible neuroprotective role of CNTF in the optic nerve head. PMID: 17563726
    35. We conclude that absence of CNTF does not increase susceptibility for neurodegenerative disorders and confirm that it does not affect onset and course of familial and sporadic ALS. PMID: 17651970
    36. Continuous expression of striatal CNTF at the dose mediated by the expression cassette used in this study was detrimental to transgenic mice with Huntington's disease. PMID: 18293418
    37. The relative treatment benefit of iloperidone compared with placebo in patients with schizophrenia is enhanced in patients homozygous G/G for the rs1800169 polymorphism of CNTF. PMID: 18303965
    38. In vivo and in vitro experiments implicate CNTF as an endogenous regulatory component of dopamine D2-receptor-dependent neurogenesis in the subventricular zone and the dentate gyrus of the hippocampus. (Review) PMID: 18524890
    39. CNTF-mediated signaling is a molecular switch for neuronal versus glial differentiation of retinal stem cells/progenitors. PMID: 18669911
    40. Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain PMID: 18728012
    41. PTP-1B constitutes a key divergent element between leptin/insulin and CNTF signaling pathways at the neuronal level. PMID: 19008309
    42. Certain SNP patterns in VDR and CNTF genes showed better improvement of parameters associated with the effects of low-resistance training using exercise machines as analyzed by comparison between SNP patterns and factor analysis. PMID: 19082510
    43. The results of this study provided further evidence that the production of ciliary neurotrophic factor by Schwann cells is markedly reduced in Charcot-Marie-Tooth type 1A neuropathy. PMID: 19525893
    44. Fusion of HIV-1 TAT to CNTF may have modified the CNTF capacity to induce intracellular signaling in hypothalamic neurons. PMID: 19573019
    45. The CNTF 1357 G --> A polymorphism explains only a small portion of the variability in the muscle strength response to training in women. PMID: 19628720
    46. An interaction between apoE3 and CNTF occurs with both delipidated apeE3 and apoE3 found within a lipoprotein particle in cerebrospinal fluid. This interaction potentiates the survival-promoting activity of CNTF for hippocampal neurons. PMID: 9236223

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    CNTF family
  • 組織特異性:
    Nervous system.
  • 數據庫鏈接:

    HGNC: 2169

    OMIM: 118945

    KEGG: hsa:1270

    STRING: 9606.ENSP00000355370

    UniGene: Hs.524920



主站蜘蛛池模板: 国产婷婷成人久久av免费高清| 亚洲中文字幕无码久久| 中文字幕乱码人妻无码久久| 1000部啪啪未满十八勿入下载| 99热99这里只有高清国产| 中文有码人妻字幕在线| 无码国产一区二区免费| 色婷婷一区二区三区四区成人网 | 99国产精品久久久久久久久久久| 亚洲成a人片在线观看www| 国产乡下三级全黄三级bd| 中国人妻被两个老外三p| 日产精品一二三区| 亚洲精品中文字幕乱码三区| 亚洲色18禁成人网站www| 无码高潮喷吹在线观看| 天天做日日做天天添天天欢公交车| 一日本道a高清免费播放| 国产成人综合欧美精品久久| 亚洲一区二区三区波多野结衣| 亚洲国产人在线播放首页| 久久无码人妻一区二区三区| 亚洲 精品 制服 校园 无码| 国产超碰人人做人人爱一二区视品| 开心婷婷五月激情综合社区| 久久久性色精品国产免费观看| 色九月亚洲综合网| 又粗又黄又爽视频免费看| 精品亚洲国产成人av| 久久久久爽爽爽爽一区老女人| av无码久久久精品免费| 日韩精品亚洲人成在线观看| 亚洲a成人片在线观看| 欧美成人h亚洲综合在线观看| 国产制服丝袜欧美在线观看| 无码一区二区三区亚洲人妻| 国产va免费精品高清在线| 亚洲色欲av无码成人专区| 风流少妇又紧又爽又丰满| 人妻丰满熟妇av无码区hd| 国产精品aⅴ在线观看|