在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CNNM2 Antibody

CNNM2 Antibody

  • 中文名稱：
    CNNM2兔多克隆抗體
  • 貨號：
    CSB-PA872518LA01HU
  • 規格：
    ￥440
  • 圖片：
    • IHC image of CSB-PA872518LA01HU diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • Immunofluorescence staining of HepG2 cells with CSB-PA872518LA01HU at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CNNM2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CNNM2
  • 別名：
    ACDP2 antibody; Ancient conserved domain containing protein 2 antibody; Ancient conserved domain protein 2 antibody; Ancient conserved domain-containing protein 2 antibody; CNNM 2 antibody; CNNM2 antibody; CNNM2_HUMAN antibody; Cyclin M2 antibody; Cyclin-M2 antibody; Metal transporter CNNM2 antibody; OTTHUMP00000020387 antibody; OTTHUMP00000020388 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Metal transporter CNNM2 protein (739-875AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，CNNM2 Antibody (CSB-PA872518LA01HU)，的標記方式是Non-conjugated。對于CNNM2 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA872518LB01HU CNNM2 Antibody, HRP conjugated ELISA
    FITC CSB-PA872518LC01HU CNNM2 Antibody, FITC conjugated
    Biotin CSB-PA872518LD01HU CNNM2 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:200-1:500
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+).
  • 基因功能參考文獻：
    1. CNNM2 single nucleotide polymorphisms association with the risk of hypertension in Chinese Han population. PMID: 30180964
    2. In this large-scale, Han Chinese population-based genetic association study for genetic susceptibility to schizophrenia of a three-gene cluster region, AS3MT-CNNM2-NT5C2, two SNPs with independent effects, rs11191419 and rs11191514, were identified. Rs11191419 is located on the 5' (potential promoter) region of AS3MT, while rs11191514 is located in one of the introns of CNNM2. PMID: 27401531
    3. this study implicates altered neural expression of BORCS7, AS3MT, and NT5C2 in susceptibility to schizophrenia arising from genetic variation at the chromosome 10q24 locus PMID: 27004590
    4. Sensitivity of CNNM2 expression to extracellular Mg(2+) depletion depends on cell type. PMID: 27068403
    5. meta-analysis of two Caucasian cohorts did not show an association between five aneurysm associated loci and sporadic brain Arteriovenous malformations. PMID: 25053769
    6. The T568I mutation causes the magnesium transporter, CNNM2, to become 'locked' in its flat form. PMID: 25184538
    7. Cells expressing mutated CNNM2 proteins did not show increased Mg(2+) uptake. PMID: 24699222
    8. This CNNM2 risk variant rs7914558 may have an impact on neural systems relevant to social cognition. PMID: 24311551
    9. Our findings suggest that the genetic variant in the CNNM2 gene could be implicated in the pathogenesis of schizophrenia through the gray matter volumetric vulnerability of the orbital regions in the inferior frontal gyri. PMID: 24160291
    10. crystals of CNNM2 belonged to space groups P2(1)2(1)2 and I222 (or I2(1)2(1)2(1)) and diffracted X-rays to 2.0 and 3.6 A resolution, respectively, using synchrotron radiation PMID: 23027747
    11. analysis of structure of CNNM2 and its post-translational modifications PMID: 22399287
    12. ACDP2 splice-variant 1 is a functional Mg2+-transporting entity per se. PMID: 20519162
    13. The CNNM2 locus is associated with serum Mg(2+) concentrations. PMID: 21397062

    顯示更多

    收起更多

  • 相關疾病：
    Hypomagnesemia 6 (HOMG6); Hypomagnesemia, seizures, and mental retardation (HOMGSMR)
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    ACDP family
  • 組織特異性：
    Widely expressed. Expressed at higher level in brain, kidney and placenta, while it is weakly expressed in skeletal muscle. In the kidney, it is expressed in the distal convoluted tubule and the thick ascending limb of Henle loop.
  • 數據庫鏈接：

    HGNC: 103

    OMIM: 607803

    KEGG: hsa:54805

    STRING: 9606.ENSP00000358894

    UniGene: Hs.643509



主站蜘蛛池模板： 88国产精品视频一区二区三区| 人人爽人人澡人人人人妻| 国产成人无码午夜视频在线播放 | 久久99精品久久久久久清纯| 国产午夜av秒播在线观看| 国产精品一区二区av不卡| 精品人妻伦一二三区久久| 国产三级在线观看免费| 精品国产肉丝袜久久| 国产成人精品日本亚洲网站| 国产精品久久久久久亚洲影视内衣| 最新永久无码av网址亚洲| 少妇爱做高清免费视频| 亚洲丁香五月激情综合| 亚洲成av人最新无码| 亚洲精品国产精品乱码不99| 国产在线视频天天综合网| 丰满无码人妻热妇无码区| 国产欧美一区二区精品久久久 | 国产精品成人a区在线观看| 久久久久久伊人高潮影院| 国产精品 精品国内自产拍| 国产精品特级露脸av毛片| 精品国际久久久久999| 狠狠躁夜夜躁人人爽天天bl| 成人乱码一区二区三区av| 草色噜噜噜av在线观看香蕉| 青草内射中出高潮| 伊人蕉影院久亚洲高清| 夜夜躁狠狠躁日日躁视频| 瑜伽裤国产一区二区三区| 人妻人人澡人人添人人爽人人玩 | 337p日本大胆欧久久| 黄瓜视频在线观看网址| 18禁白丝喷水视频www视频| 日韩去日本高清在线| 最新亚洲中文av在线不卡| 性色av无码一区二区三区人妻| 东京热人妻无码一区二区av| 97se亚洲国产综合自在线| 国产女人18毛片水真多|