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  4. CNN3 Antibody, HRP conjugated

CNN3 Antibody, HRP conjugated

  • 中文名稱：
    CNN3兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA005657LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CNN3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CNN3
  • 別名：
    Acidic calponin 3 antibody; acidic isoform antibody; Calponin 3 acidic antibody; Calponin 3 antibody; Calponin acidic antibody; Calponin acidic isoform antibody; Calponin antibody; Calponin-3 antibody; Calponin3 antibody; CNN 3 antibody; Cnn3 antibody; CNN3_HUMAN antibody; dJ639P13.2.2 antibody; OTTHUMP00000012470 antibody; OTTHUMP00000012471 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Calponin-3 protein (2-329AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
  • 基因功能參考文獻：
    1. These results reveal the importance of the MEKK1-calponin-3 signaling pathway to cell contractility. PMID: 27528401
    2. overexpressed CNN3 during sonic vibration increases expression of glutamate receptors and promotes functional neural differentiation of human umbilical cords-mesenchymal stem cells. PMID: 26175098
    3. CNN3 as a new pro-invasive protein in trophoblast cells that is induced under low oxygen conditions. PMID: 25050546
    4. Participates in actin stress fiber remodeling PMID: 23545751
    5. The mRNA and protein level of calponin-3 were increase expression in brain in patiens with epilepsy. PMID: 22119193
    6. Results indicate that CNN3 regulates actin cytoskeleton rearrangement which is required for the plasma membranes of trophoblasts to become fusion competent. PMID: 20861310
    7. These results suggest a role of calponin 3 in the regulation of Bone morphogenetic proteins -dependent cellular responses. PMID: 17825283
    8. Gene rearrangements of CNN3 is associated with mucosa-associated lymphoid tissue lymphoma. PMID: 18927281

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  • 蛋白家族：
    Calponin family
  • 組織特異性：
    Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.
  • 數據庫鏈接：

    HGNC: 2157

    OMIM: 602374

    KEGG: hsa:1266

    STRING: 9606.ENSP00000359225

    UniGene: Hs.483454



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