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  4. CMBL Antibody

CMBL Antibody

  • 中文名稱：
    CMBL兔多克隆抗體
  • 貨號：
    CSB-PA005602GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CMBL
  • 別名：
    Carboxymethylenebutenolidase homolog (Pseudomonas) antibody; Carboxymethylenebutenolidase homolog antibody; cmbl antibody; CMBL_HUMAN antibody; FLJ23617 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human CMBL
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cysteine hydrolase. Can convert the prodrug olmesartan medoxomil into its pharmacologically active metabolite olmerstatan, an angiotensin receptor blocker, in liver and intestine. May also activate beta-lactam antibiotics faropenem medoxomil and lenampicillin.
  • 基因功能參考文獻：
    1. By comparing the enzyme kinetics and chemical inhibition properties between the recombinant protein and tissue preparations, CMBL was shown to be the primary olmesartan medoxomil bioactivating enzyme in the liver and intestine. PMID: 20177059
  • 亞細胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Dienelactone hydrolase family
  • 組織特異性：
    Widely expressed, with highest levels in liver, followed by kidney, small intestine and colon. Present in liver and intestine (at protein level).
  • 數據庫鏈接：

    HGNC: 25090

    OMIM: 613379

    KEGG: hsa:134147

    STRING: 9606.ENSP00000296658

    UniGene: Hs.192586



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