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  4. CLSTN3 Antibody, HRP conjugated

CLSTN3 Antibody, HRP conjugated

  • 中文名稱：
    CLSTN3兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA871555LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CLSTN3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CLSTN3
  • 別名：
    CLSTN3 antibody; CS3 antibody; KIAA0726Calsyntenin-3 antibody; Alcadein-beta antibody; Alc-beta antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Calsyntenin-3 protein (197-408AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May modulate calcium-mediated postsynaptic signals. Complex formation with APBA2 and APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the retardation of intracellular APP maturation.
  • 基因功能參考文獻：
    1. ApoE expression attenuated intracellular trafficking of APP and Alcbeta PMID: 26213366
    2. structure of Calsyntenin 3 and its interaction with neurexin 1alpha PMID: 25352602
    3. The C-terminal fragment but not full-length Cst-3 accumulated in dystrophic neurites surrounding amyloidbeta plaques in Tg2576 mouse and Alzheimer disease brains. PMID: 23499467
    4. Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation [alcalpha1, alcbeta, alcgamma] PMID: 15037614
  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane. Golgi apparatus membrane. Cell junction, synapse, postsynapse. Cell projection, dendrite.
  • 組織特異性：
    According to PubMed:12498782, expressed predominantly in the brain and in kidney. Low levels in heart, skeletal muscle, liver, placenta, pancreas and lung. According to PubMed:12972431, predominant expression in brain, and only marginal in kidney. In brai
  • 數據庫鏈接：

    HGNC: 18371

    OMIM: 611324

    KEGG: hsa:9746

    UniGene: Hs.535378



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