在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CLPB Antibody

CLPB Antibody

  • 中文名稱：
    CLPB兔多克隆抗體
  • 貨號：
    CSB-PA884428LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: CLPB antibody at 5μg/ml + 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 79, 76, 73, 75, 58 kDa
      Observed band size: 79 kDa
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA884428LA01HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品描述：

    Rabbits were immunized to generate the CLPB polyclonal antibody, which is specifically designed to recognize and bind to the human CLPB protein. The development of this antibody involved using a recombinant human CLPB protein that consisted of amino acids 1-350 as an immunogen. The resulting CLPB antibody was then purified using protein G affinity chromatography, achieving a purity level of up to 95%.

    This antibody only reacts with human samples. It has been extensively tested in various experimental settings, such as ELISA, WB, and IHC, to investigate the expression, localization, and activity of the CLPB protein in different contexts. These tests have demonstrated the ability of the CLPB polyclonal antibody to effectively identify and detect the CLPB protein in various experimental conditions.

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CLPB Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CLPB
  • 別名：
    Caseinolytic peptidase B antibody; Caseinolytic peptidase B protein homolog antibody; clpB antibody; ClpB caseinolytic peptidase B homolog (E. coli) antibody; ClpB caseinolytic peptidase B homolog antibody; CLPB_HUMAN antibody; FLJ13152 antibody; HSP78 antibody; SKD3 antibody; Suppressor of potassium transport defect 3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Caseinolytic peptidase B protein homolog protein (1-350AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，CLPB Antibody (CSB-PA884428LA01HU)，的標記方式是Non-conjugated。對于CLPB Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA884428LB01HU CLPB Antibody, HRP conjugated ELISA
    FITC CSB-PA884428LC01HU CLPB Antibody, FITC conjugated
    Biotin CSB-PA884428LD01HU CLPB Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May function as a regulatory ATPase and be related to secretion/protein trafficking process. Involved in mitochondrial-mediated antiviral innate immunity, activates RIG-I-mediated signal transduction and production of IFNB1 and proinflammatory cytokine IL6.
  • 基因功能參考文獻：
    1. The neonatal presentation of CLPB deficiency predicts the course of disease in later life, which is extremely important for counselling. PMID: 28687938
    2. Case Reports: bi-allelic CLPB mutations cause cataract, renal cysts, nephrocalcinosis and 3-methylglutaconic aciduria, a novel disorder of mitochondrial protein disaggregation. PMID: 25595726
    3. Disruption of CLPB is associated with congenital microcephaly, severe encephalopathy and 3-methylglutaconic aciduria PMID: 25650066
    4. ClpB can passively thread soluble denatured proteins. PMID: 25288401
    5. Mutations in CLPB define a syndrome with intellectual disability, congenital neutropenia, progressive brain atrophy, movement disorder, cataracts, and 3-methylglutaconic aciduria. PMID: 25597510
    6. CLPB is proposed to function as a mitochondrial chaperone involved in disaggregation of misfolded proteins, resulting from stress such as heat denaturation. PMID: 25597511
    7. ClpB-DnaK reactivated all aggregated fusion proteins with similar efficiency, without unfolding native domains, demonstrating that partial threading of the misfolded moiety is sufficient to solubilize aggregates. PMID: 18488042
    8. formation of the DnaK-ClpB bichaperone network is a three step process PMID: 19698713

    顯示更多

    收起更多

  • 相關疾病：
    3-methylglutaconic aciduria with cataracts, neurologic involvement and neutropenia (MEGCANN)
  • 亞細胞定位：
    Mitochondrion intermembrane space.
  • 蛋白家族：
    ClpA/ClpB family
  • 組織特異性：
    Widely expressed (at protein level). Expressed in fetal, as well as in adult tissues, with highest levels in adult brain, including thalamus, hippocampus, occipital cortex and parietal cortex. Low expression in granulocytes.
  • 數據庫鏈接：

    HGNC: 30664

    OMIM: 616254

    KEGG: hsa:81570

    STRING: 9606.ENSP00000294053

    UniGene: Hs.523877



主站蜘蛛池模板： 国模大尺度啪啪| 天堂www中文在线资源| 国产午夜无码视频在线观看| 久久精品农村毛片| 137日本免费肉体摄影| 人妻熟妇乱又伦精品hd| 亚洲人成电影网站色www两男一女| 国产-第1页-浮力影院| 国产粉嫩嫩00在线正在播放| 四库影院永久四虎精品国产 | 亚洲欧美色中文字幕在线| 女人大荫蒂毛茸茸视频| 天堂aⅴ无码一区二区三区| 国产精品美女久久久m| 特级毛片a片久久久久久| 亚洲精品成人无码中文毛片不卡| 国产免费人成视频尤勿视频| a欧美爰片久久毛片a片| 日本成本人片免费网站 | 99久久久无码国产精品古装| 国产精品三级av及在线观看| 中文字幕在线精品视频| 国产98色在线 | 国产| 2020国产欧洲精品网站| 亚洲国产品综合人成综合网站| 少妇粗大进出白浆嘿嘿视频| 国产精品一卡二卡三卡| 亚洲精品久久久久久久久久久捆绑| 午夜一区二区亚洲福利| 中文字幕无码av波多野吉衣| 欲求不满邻居的爆乳在线播放| 国产成+人+综合+亚洲欧美 | 一本色道无码不卡在线观看| 中文乱码免费一区二区| 在线看片免费人成视频国产片| 毛片内射久久久一区| 欧美人与禽zoz0性伦交| 波多老师无码av中字专区| 国产一起色一起爱| 女人爽到高潮免费视频大全| 亚洲综合无码中文字幕第2页|