在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CLEC4D Antibody

  • 中文名稱:
    CLEC4D兔多克隆抗體
  • 貨號:
    CSB-PA162407
  • 規格:
    ¥1100
  • 圖片:
    • Gel: 10%SDS-PAGE,Lysate: 40 μg,,Primary antibody: CSB-PA162407(CLEC4D Antibody) at dilution 1/123 dilution,Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution,Exposure time: 1 minute
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    CLEC4D
  • 別名:
    C type (calcium dependent; carbohydrate recognition domain) lectin; superfamily member 8 antibody; C type lectin domain family 4; member D antibody; C type lectin like receptor 6 antibody; C type lectin receptor antibody; C type lectin superfamily member 8 antibody; C-type lectin domain family 4 member D antibody; C-type lectin superfamily member 8 antibody; C-type lectin-like receptor 6 antibody; CLC4D_HUMAN antibody; CLEC 6 antibody; CLEC-6 antibody; Clec4d antibody; CLEC6 antibody; CLECSF8 antibody; lectin; C type; superfamily member 8 antibody; Macrophage C type lectin antibody; MCL antibody; MGC40078 antibody; MPCL antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Fusion protein of Human CLEC4D
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Calcium-dependent lectin that acts as a pattern recognition receptor (PRR) of the innate immune system: recognizes damage-associated molecular patterns (DAMPs) of pathogen-associated molecular patterns (PAMPs) of bacteria and fungi. The PAMPs include alpha-mannans on C.albicans hypheas and mycobacterial trehalose 6,6'-dimycolate (TDM). Interacts with signaling adapter Fc receptor gamma chain/FCER1G, likely via CLEC4E, to form a functional complex in myeloid cells. Binding of mycobacterial TDM or C.albicans alpha-mannans to this receptor complex leads to phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of FCER1G, triggering activation of SYK, CARD9 and NF-kappa-B, consequently driving maturation of antigen-presenting cells and shaping antigen-specific priming of T-cells toward effector T-helper 1 and T-helper 17 cell subtypes. The heterodimer formed with CLEC6A is active against fungal infection. Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for clearance of the antigen, or for processing and further presentation to T-cells.
  • 基因功能參考文獻:
    1. Results show the molecular mechanism of glycolipid recognition through C-type lectin receptors, which may provide clues to rational design for effective adjuvants. PMID: 24101491
    2. CLECSF8 functions as an activation receptor on myeloid cells and associates with a novel adaptor molecule PMID: 22689578
    3. Cross-linking of the receptor leads to a rapid internalization suggesting that CLECSF8 constitutes and endocytic receptor. PMID: 14971047
  • 亞細胞定位:
    Cell membrane; Single-pass type II membrane protein.
  • 組織特異性:
    Expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression is confined mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma.
  • 數據庫鏈接:

    HGNC: 14554

    OMIM: 609964

    KEGG: hsa:338339

    STRING: 9606.ENSP00000299665

    UniGene: Hs.351811



主站蜘蛛池模板: 欧美激情精品成人一区| 成人国产欧美大片一区| 成年午夜精品久久久精品| ww欧日韩视频高清在线| 人妻人人看人妻人人添| 波多野结衣办公室33分钟| 国产强被迫伦姧在线观看无码 | 无码国产玉足脚交极品网站| 四虎影库久免费视频| 久久人人玩人妻潮喷内射人人| 国产麻豆剧果冻传媒一区 | 4444亚洲人成无码网在线观看 | 97久久精品人妻人人搡人人玩| 国产无遮挡又爽又刺激的视频老师| 四虎国产精品一区二区| 99久在线国内在线播放免费观看 | 老熟女老太婆爽| 黑人巨大精品欧美黑寡妇| 欧美野外疯狂做受xxxx高潮 | 精品少妇无码一区二区三批| 日本中文字幕在线| 日韩av高清无码| 亚洲丁香婷婷综合久久| 亚洲精品乱码久久久久久自慰| 欧美日韩欧美| 亚洲 丝袜 制服 欧美 另类| 亚洲一本一道一区二区三区| 国产二级一片内射视频插放| 精品久久久久久无码专区| 动漫av一区二区在线观看| 夜色爽爽影院18禁妓女影院| 国产日产韩国精品视频| 四房播播开心五月| 国产精品色拉拉| 人妻av无码专区| 女人裸体做爰免费视频| 欧洲亚洲1卡二卡三卡2021 | 护士脱了内裤让我爽了一夜视频 | 国产精品爽爽久久久久久竹菊| 色舞月亚洲综合一区二区| 欧美三级在线播放|