在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CIAO1 Antibody

CIAO1 Antibody

  • 中文名稱：
    CIAO1兔多克隆抗體
  • 貨號：
    CSB-PA005423GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CIAO1
  • 別名：
    CIAO1 antibody; CIA1 antibody; WDR39Probable cytosolic iron-sulfur protein assembly protein CIAO1 antibody; WD repeat-containing protein 39 antibody
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human CIAO1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. As a CIA complex component, interacts specifically with CIAO2A or CIAO2B and MMS19 to assist different branches of iron-sulfur protein assembly, depending of its interactors. The complex CIAO1:CIAO2B:MMS19 binds to and facilitates the assembly of most cytosolic-nuclear Fe/S proteins. CIAO1:CIAO2A specifically matures ACO1 and stabilizes IREB2. Seems to specifically modulate the transactivation activity of WT1. As part of the mitotic spindle-associated MMXD complex it may play a role in chromosome segregation.
  • 基因功能參考文獻：
    1. Data suggest that CIA2B and MMS19 physically interact with C-terminus of viperin/RSAD2; CIAO1 appears to function as primary viperin-interacting protein; CIA2A binds to N-terminus of viperin in CIAO1-, CIA2B-, and MMS19-independent fashion. (CIA2B = metallochaperone CIA2B/FAM96B; MMS19 = transcription factor MMS19; CIAO1 = cytosolic iron-sulfur assembly component 1; CIA2A = metallochaperone CIA2A/Fam96a) PMID: 28615450
    2. POLE1 is phosphorylated at serine-1940 after DNA damage and interacts with the iron-sulfur complex chaperones CIAO1 and MMS19. PMID: 27235625
    3. These data suggest that viperin requires CIAO1 for [4Fe-4S] cluster assembly, and acts through an enzymatic, Fe-S cluster- and SAM-dependent mechanism to inhibit viral RNA synthesis. PMID: 24245804
    4. CIA2B-CIA1-MMS19 and CIA2A-CIA1 assist different branches of Fe/S protein assembly and intimately link this process to cellular iron regulation via IRP1 Fe/S cluster maturation and IRP2 stabilization. PMID: 23891004
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    WD repeat CIA1 family
  • 數據庫鏈接：

    HGNC: 14280

    OMIM: 604333

    KEGG: hsa:9391

    STRING: 9606.ENSP00000418287

    UniGene: Hs.12109



主站蜘蛛池模板： 欧美精品无码一区二区三区| 国产清纯美女遭强到高潮| 产精品视频在线观看免费| 久久人人爽人人爽人人片av不| 暖暖 在线 日本 免费 中文| 麻豆精产一二三产区| 亚洲精品国产高清在线观看| 欧美综合天天夜夜久久| 亚洲中文字幕久久无码| 亚洲一区二区三区在线观看网站| 女人摸下面自熨视频在线播放| 国产精品久久久久久久久久免费看| 欧美在线 | 亚洲| 少妇激情av一区二区三区| 欧美成人形色生活片| 精品欧美一区二区三区久久久| 2020久久香蕉国产线看观看| 婷婷网亚洲色偷偷男人的天堂| 免费看成人毛片无码视频| 久久综合九色综合欧美98| 色综合av男人的天堂伊人 | 欧美成人精品三级网站视频| 久久精品亚洲中文字幕无码网站| 国产中文欧美日韩在线| 人妻精品制服丝袜久久久| 久久国产人妻一区二区免费 | 在线精品国产大象香蕉网| 人妻少妇精品久久久久久| 久久久久99人妻一区二区三区| 亚洲国产欧美日韩精品一区二区三区| 亚洲午夜精品久久久久久浪潮| 欧美日韩在线第一页免费观看| 乱码视频午夜间在线观看| 野花社区www视频最新资源| 日日碰狠狠躁久久躁综合小说| 久在线精品视频线观看| 波多野无码黑人在线播放| 中文字幕人妻互换av久久| 一本色道无码道dvd在线观看| 亚洲欧美日韩国产另类电影| 精品无码国产一区二区三区av|