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CHRM5 Antibody

  • 中文名稱(chēng)：
    CHRM5兔多克隆抗體
  • 貨號(hào)：
    CSB-PA005385LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Mouse liver tissue, Mouse kidney tissue, Mouse brain tissue
      All lanes: CHRM5 antibody at 3.5μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 61 kDa
      Observed band size: 61 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA005385LA01HU at dilution of 1:100
    • Immunofluorescent analysis of A549 cells using CSB-PA005385LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) CHRM5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    CHRM5; Muscarinic acetylcholine receptor M5
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Muscarinic acetylcholine receptor M5 protein (220-427AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，CHRM5 Antibody (CSB-PA005385LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于CHRM5 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA005385LB01HU CHRM5 Antibody, HRP conjugated ELISA
    FITC CSB-PA005385LC01HU CHRM5 Antibody, FITC conjugated
    Biotin CSB-PA005385LD01HU CHRM5 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover.
  • 基因功能參考文獻(xiàn)：
    1. Immunological stimulation leads to M5 mAChR gene expression in lymphocytes. PMID: 12675126
    2. direct evidence suggesting that the M5 muscarinic receptor gene combined with the alpha7-nicotinic receptor gene may be linked to schizophrenia PMID: 15292665
    3. mAChR subtypes (m1 to m5)presents in human scleral fibroblasts at both mRNA and protein levels. PMID: 16877267
    4. the first study to show an association between CHRM5 and substance use in humans PMID: 17608938
  • 亞細(xì)胞定位：
    Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family, Muscarinic acetylcholine receptor subfamily, CHRM5 sub-subfamily
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 1954

    OMIM: 118496

    KEGG: hsa:1133

    STRING: 9606.ENSP00000372750

    UniGene: Hs.584747



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