在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. CHRDL1 Antibody

CHRDL1 Antibody

  • 中文名稱：
    CHRDL1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA866283LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Hela whole cell lysate, A549 whole cell lysate
      All lanes: CHRDL1 antibody at 5.7µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 52, 44, 53 kDa
      Observed band size: 52 kDa
    • IHC image of CSB-PA866283LA01HU diluted at 1:200 and staining in paraffin-embedded human endometrial cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) CHRDL1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CHRDL1
  • 別名：
    CHL antibody; chordin like 1 antibody; Chordin-like protein 1 antibody; CHRDL1 antibody; CRDL1_HUMAN antibody; dA141H5.1 antibody; neuralin 1 antibody; Neuralin-1 antibody; Neurogenesin-1 antibody; NRLN1 antibody; Ventroptin antibody; VOPT antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Chordin-like protein 1 protein (92-237AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，CHRDL1 Antibody (CSB-PA866283LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于CHRDL1 Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA866283LB01HU CHRDL1 Antibody, HRP conjugated ELISA
    FITC CSB-PA866283LC01HU CHRDL1 Antibody, FITC conjugated
    Biotin CSB-PA866283LD01HU CHRDL1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:200-1:500
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Antagonizes the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal differentiation of neural stem cells in the brain by preventing the adoption of a glial fate. May play a crucial role in dorsoventral axis formation. May play a role in embryonic bone formation. May also play an important role in regulating retinal angiogenesis through modulation of BMP4 actions in endothelial cells. Plays a role during anterior segment eye development.
  • 基因功能參考文獻(xiàn)：
    1. Finally, in vivo experiments confirmed that CHRDL1 acted as a tumor suppressor gene in suppressing tumor growth and metastasis PMID: 28423564
    2. Results show that Chrdl1 expression is upregulated in numerous breast cancer cells following TGF-beta stimulation and demonstrated that Chrdl1 acts as an inhibitor of BMP4-induced migration and invasion. PMID: 26976638
    3. These studies have identified and validated new factors enriched in juvenile chondrocytes as compared to adult chondrocytes including secreted extracellular matrix factors chordin-like 1 (CHRDL1) and microfibrillar-associated protein 4 (MFAP4). PMID: 26955889
    4. We provide the initial confirmation that X-linked megalocornea is associated with mutations in the CHRDL1 gene. PMID: 24073597
    5. CHRDL1 plays a key role in cornea homeostasis as evidenced by disease causing mutations in X-linked megalocornea. PMID: 25712132
    6. The detection of mutations in the CHRDL1 gene is useful for differential diagnosis with different forms of megalocornea. PMID: 26020825
    7. Novel CHRDL1 mutations in ten families with X-linked megalocornea, are reported. PMID: 25093588
    8. CHRDL1 is expressed in the developing human cornea and anterior segment in addition to the retina. PMID: 22284829
    9. Hypoxia-induced upregulation of CHL-1 alters the homeostatic balance between BMP-4 and VEGF to synergize with VEGF in driving retinal angiogenesis. PMID: 18587495
    10. reports the cloning of chick ventroptin and its importance in topographic retinotectal projection PMID: 11441185

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Megalocornea 1, X-linked (MGC1)
  • 亞細(xì)胞定位：
    Secreted.
  • 組織特異性：
    Expressed in the developing cornea and in the eye anterior segment in addition to the retina. Differentially expressed in the fetal brain. There is high expression in cerebellum and neocortex. Expressed in retinal pericytes.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29861

    OMIM: 300350

    KEGG: hsa:91851

    STRING: 9606.ENSP00000361112

    UniGene: Hs.496587



主站蜘蛛池模板： 真人做人试看60分钟免费视频| 少妇系列之白嫩人妻| 日本极品少妇xxxx| 国产精品被窝福利一区| 被窝影院午夜无码国产| 军人粗大的内捧猛烈进出视频| 国产又粗又猛又大爽又黄| 女人被做到高潮免费视频| 日本熟妇人妻videos| 丰满少妇被猛烈进入试看| 天天摸夜夜摸夜夜狠狠摸| 国精品人妻无码一区二区三区d3| 97国产超碰一区二区三区| 日韩少妇人妻vs中文字幕| 亚洲精品久久久久久久久久吃药| 9420免费高清在线观看视频| 亚洲成a人片在线观看天堂| 国产精品高清网站| 韩国美女视频黄是免费| 成 人色 网 站 欧美大片在线观看| 国产成人精品精品日本亚洲| 亚洲国产精品一区二区www| 经典国产乱子伦精品视频| 最新国产aⅴ精品无码| 狠狠色丁香久久婷婷综合蜜芽五月| 国产三级av在线播放| 亚洲一本大道av久在线播放| 国产成人a∨麻豆精品| 激情爆乳一区二区三区| 国产精品无码成人午夜电影| 国产成人精品永久免费视频| 性暴力欧美猛交在线播放| 人妻无码视频一区二区三区 | 性夜影院午夜看片| 国产av亚洲精品久久久久久小说| 黄a大片av永久免费| 7777精品久久久大香线蕉| 国产精品美女久久久m| 人妻丰满熟妇av无码区 | 国精产品999一区二区三区有限| 欧洲专线一区二区三区|