在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CHMP6 Antibody

  • 中文名稱:
    CHMP6兔多克隆抗體
  • 貨號:
    CSB-PA846622LA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA846622LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA846622LA01HU at dilution of 1:100
    • Western Blot
      Positive WB detected in: Rat lung tissue
      All lanes: CHMP6 antibody at 3µg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 24 kDa
      Observed band size: 24 kDa
    • Immunohistochemistry analysis of human melanoma using CSB-PA846622LA01HU at dilution of 1:100
    • Immunohistochemistry analysis of human brain tissue using CSB-PA846622LA01HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) CHMP6 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    Charged multivesicular body protein 6 antibody; chmp6 antibody; CHMP6_HUMAN antibody; Chromatin modifying protein 6 antibody; Chromatin-modifying protein 6 antibody; FLJ11749 antibody; hVps 20 antibody; hVps20 antibody; novel SNF7 protein antibody; OTTMUSP00000004363 antibody; RGD1565325 antibody; RP24 225K18.4 antibody; Vacuolar protein sorting associated protein 20 antibody; Vacuolar protein sorting-associated protein 20 antibody; Vps 20 antibody; Vps20 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Rat
  • 免疫原:
    Recombinant Human Charged multivesicular body protein 6 protein (2-201AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,CHMP6 Antibody (CSB-PA846622LA01HU),的標記方式是Non-conjugated。對于CHMP6 Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA846622LB01HU CHMP6 Antibody, HRP conjugated ELISA
    FITC CSB-PA846622LC01HU CHMP6 Antibody, FITC conjugated
    Biotin CSB-PA846622LD01HU CHMP6 Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. In the ESCRT-III complex, it probably serves as an acceptor for the ESCRT-II complex on endosomal membranes.
  • 基因功能參考文獻:
    1. Taken together, these data suggest an active role for ESCRT-II and CHMP6 in ESCRT-mediated abscission PMID: 25232011
    2. Purified VPS-20 exhibits an open extended conformation, irrespective of ESCRT-II binding. PMID: 25588614
    3. silencing CHMP6 and VPS4A also blocked epidermal growth factor receptor (EGFR) recycling PMID: 22231449
    4. In this study, we found that overexpression of chromatin modifying protein 6 (CHMP6) induced cell death by a series of experiments. PMID: 19270365
    5. Results describe the mapping of multivesicular bodies with the second winged helix domain of human ESCRT-II subunit VPS25 and the first helix of ESCRT-III subunit VPS20. PMID: 19686684

    顯示更多

    收起更多

  • 亞細胞定位:
    Endomembrane system. Endosome membrane; Lipid-anchor. Late endosome membrane. Membrane; Lipid-anchor. Note=Localizes to endosomal membranes.
  • 蛋白家族:
    SNF7 family
  • 組織特異性:
    Ubiquitously expressed.
  • 數據庫鏈接:

    HGNC: 25675

    OMIM: 610901

    KEGG: hsa:79643

    STRING: 9606.ENSP00000317468

    UniGene: Hs.514560



主站蜘蛛池模板: 日韩在线一区二区不卡视频| 久久无码人妻精品一区二区三区| 国产成人亚洲精品| 88国产精品欧美一区二区三区| 久久亚洲一区二区三区舞蹈| 亚洲一卡一卡二新区迎热烈讨论| 无码一区二区免费波多野播放搜索 | 中文字幕无码精品亚洲35| 四虎成人精品国产永久免费无码| 在线日韩日本国产亚洲| 在线天堂资源www在线中文| 国语对白嫖老妇胖老太| 熟妇高潮一区二区三区| 国产精品美女被遭强扒开双腿| 亚洲熟妇色xxxxx欧美老妇| 欧美人与动人物姣配xxxx | 国产萌白酱喷水视频在线播放| 亚洲男男无套gv大学生| 四虎永久在线精品免费网站| 毛片无码一区二区三区a片视频| 国产精品香港三级国产av| 亚洲一区二区三区波多野结衣| 亚洲伊人久久精品酒店| 啦啦啦www在线观看免费视频 | 国产高潮抽搐喷水高清| 亚洲日韩中文字幕久热| 国产精品午夜小视频观看| 大桥久未无码吹潮在线观看| 狂野欧美性猛xxxx乱大交 | 四川丰满少妇被弄到高潮| 午夜福利国产成人无码gif动图 | 久久综合九色综合欧洲98| 777午夜福利理论电影网| 人妻内射一区二区在线视频 | 欧美日本免费一区二区三区| 92电影网午夜福利| 大香线蕉伊人超碰| 无码国产精品一区二区vr| 日韩精品视频一区二区三区| 欧美成人看片一区二区| 四虎永久在线精品884aa|