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  4. CHML Antibody

CHML Antibody

  • 中文名稱：
    CHML兔多克隆抗體
  • 貨號：
    CSB-PA003958
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using REP-2 Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    CHML
  • 別名：
    CHM like antibody; Chml antibody; Choroideraemia like protein antibody; Choroideraemia-like protein antibody; Choroideremia like (Rab escort protein 2) antibody; Choroideremia like antibody; Choroideremia like protein antibody; Rab escort protein 2 antibody; Rab proteins geranylgeranyltransferase component A 2 antibody; RAE2_HUMAN antibody; REP 2 antibody; REP-2 antibody; REP2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human REP-2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane. Less effective than CHM in supporting prenylation of Rab3 family.
  • 基因功能參考文獻：
    1. Polymorphisms in the OPN3 and CHML genes are associated with asthma and atopic asthma. PMID: 18344558
  • 亞細胞定位：
    Cytoplasm, cytosol.
  • 蛋白家族：
    Rab GDI family
  • 數據庫鏈接：

    HGNC: 1941

    OMIM: 118825

    KEGG: hsa:1122

    STRING: 9606.ENSP00000355511

    UniGene: Hs.654545



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