在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

CHKB Antibody

  • 中文名稱:
    CHKB兔多克隆抗體
  • 貨號:
    CSB-PA020258
  • 規(guī)格:
    ¥2024
  • 圖片:
    • Western blot analysis of extracts from HepG2 cells and A549 cells, using CHKB antibody.
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) CHKB Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    CHKB
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from internal of Human CHKB.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 克隆類型:
    Polyclonal
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis.
  • 基因功能參考文獻:
    1. findings suggest that CKbeta, in concert with CKalpha, and depending on its phosphorylation status, might play a critical role as a druggable target in carcinogenesis PMID: 27149373
    2. The whole exome sequencing revealed a novel homozygous missense mutation in the Choline Kinase-Beta (CHKB) gene in exon 9. PMID: 27123443
    3. A new form of congenital muscular dystrophy with multisystem involvement and characteristic mitochondrial structural changes, due to choline kinase beta gene defects has been characterized. PMID: 26067811
    4. A novel silent variant in the choline kinase beta causing muscular dystrophy. PMID: 25740612
    5. Its mutations cause congenital muscular dystrophy.[Review] PMID: 24291895
    6. study identified a novel haplotype consisting of the indel variation, which had not been detected in previous studies in Japanese and Korean populations, and observed four single-nucleotide polymorphisms in CHKB/CPT1B PMID: 24571861
    7. CHKB encodes choline kinase beta, an enzyme that catalyzes the first de-novo biosynthetic step of phosphatidylcholine, the most abundant phospholipid in the eukaryotic membrane [review] PMID: 23945283
    8. CHKB activity was reduced in all three patients, significant reduction in choline:N-acetyl aspartate and choline:creatine ratios in keeping with a general decrease in the amount of choline and phosphocholine-based substrate PMID: 23692895
    9. The study extends on the observation of a strong multiethnic association of polymorphisms in the TCRA and P2RY11 with narcolepsy, but does not confirm the association of CPT1B/CHKB (rs5770917) in the Chinese population. PMID: 22177342
    10. homozygous or compound heterozygous mutations in the gene encoding choline kinase beta were identified in individulas with congenital muscular dystrophy. PMID: 21665002
    11. A single nucleotide polymorphism located between CPT1B and CHKB, was associated with narcolepsy in Japanese (rs5770917[C], odds ratio (OR) = 1.79, combined P = 4.4 x 10(-7)) and other ancestry groups (OR = 1.40, P = 0.02). PMID: 18820697
    12. Japanese CNS hypersomnias (essential hypersomnia: EHS) other than narcolepsy with cataplexy was significantly associated with SNP rs5770917 (located between CPT1B and CHKB) and HLA-DRB1*1501-DQB1*0602 haplotype PMID: 19404393

    顯示更多

    收起更多

  • 蛋白家族:
    Choline/ethanolamine kinase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 1938

    OMIM: 612395

    KEGG: hsa:1120

    STRING: 9606.ENSP00000384400

    UniGene: Hs.654827



主站蜘蛛池模板: 亚洲欧美综合一区二区三区| 香港三日本三级少妇三级66| 欧美午夜特黄aaaaaa片| 人人鲁人人莫人人爱精品| 午夜福利不卡在线视频| 67194熟妇在线直接进入| 成人片黄网站色大片免费毛片| 女人和拘做爰正片视频| 久久久橹橹橹久久久久高清| 少妇高潮惨叫久久久久电影| 国产免费牲交视频| 中文字幕无码一区二区免费| 火箭视频在线观看精品| 三级无码在钱av无码在钱| 少妇久久久久久被弄高潮| 最新国产在线拍揄自揄视频| 一边吃奶一边摸做爽视频| 久久精品人妻少妇一区二区三区| 国产在线无码制服丝袜无码| 国自产拍偷拍精品啪啪av| 特级aaaaaaaaa毛片免费视频| 天天躁日日躁狠狠躁超碰97| 亚洲日韩在线a视频在线观看 | 欧美性色老妇人| 国产偷窥熟女精品视频大全| 欧美人与动牲交xxxxbbbb| 午夜福利18以下勿进免费| 亚洲 欧洲 日韩 综合av| 中文字幕丰满乱子伦无码专区| 丰满少妇被粗大的猛烈进出视频| 爆乳一区二区三区无码| 无码人妻一区二区三区免费手机| 青娱乐极品视觉盛宴国产视频| 美女裸奶100%无遮挡免费网站| 无遮挡十八禁污污污网站| 搡老岳熟女国产熟妇| 国产精品久久久福利| 国产精品香蕉在线的人| 欧美精品videossex另类日本| 国产一区二区三区无码免费| 久久婷婷五月综合色丁香|