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  4. CETN1 Antibody

CETN1 Antibody

  • 中文名稱：
    CETN1兔多克隆抗體
  • 貨號：
    CSB-PA613263DSR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: CETN1 antibody at 2.7 μg/ml + Mouse gonadal tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 20 kDa
      Observed band size: 20 kDa
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA613263DSR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CETN1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CETN1
  • 別名：
    Caltractin antibody; Caltractin isoform 2 antibody; CEN 1 antibody; CEN1 antibody; Centrin EF hand protein 1 antibody; Centrin-1 antibody; Centrin1 antibody; CETN 1 antibody; CETN antibody; CETN1 antibody; CETN1_HUMAN antibody; EF hand protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Centrin-1 protein (1-172AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Plays a fundamental role in microtubule-organizing center structure and function. Plays a role in sperm cilia formation.
  • 基因功能參考文獻：
    1. important spectral and hydrodynamic characteristics of human Centrin-1, accounting that HsCentrin-1 has moderate affinity for Ca(2+). Centrin-1 does not gain structure as seen by far- and near-UV circular dichroism, rather there is a loss of ellipticity, though inconsiderable upon binding Ca(2+). PMID: 27235176
    2. A chirality change in XPC- and Sfi1-derived peptides affects their affinity for centrin. PMID: 26923803
    3. CETN1 is overexpressed in breast cancer tissue and promotes cells'proliferation, tumor growth and metastasis. PMID: 25261648
    4. These data demonstrate a functional role for CaM binding to CP110 and suggest that CP110 cooperates with CaM and centrin to regulate progression through cytokinesis. PMID: 16760425
  • 亞細胞定位：
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cell projection, cilium.
  • 蛋白家族：
    Centrin family
  • 數據庫鏈接：

    HGNC: 1866

    OMIM: 603187

    KEGG: hsa:1068

    STRING: 9606.ENSP00000319052

    UniGene: Hs.122511



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