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CES3 Antibody

  • 中文名稱：
    CES3兔多克隆抗體
  • 貨號：
    CSB-PA005260LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA005260LA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA005260LA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA005260LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) CES3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    CES3
  • 別名：
    Carboxylesterase 3 antibody; CES 3 antibody; Ces3 antibody; ES3 antibody; EST3_HUMAN antibody; FLJ21736 antibody; Liver carboxylesterase 31 homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Carboxylesterase 3 protein (65-233AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，CES3 Antibody (CSB-PA005260LA01HU)，的標記方式是Non-conjugated。對于CES3 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA005260LB01HU CES3 Antibody, HRP conjugated ELISA
    FITC CSB-PA005260LC01HU CES3 Antibody, FITC conjugated
    Biotin CSB-PA005260LD01HU CES3 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows low catalytic efficiency for hydrolysis of CPT-11 (7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin), a prodrug for camptothecin used in cancer therapeutics.
  • 基因功能參考文獻：
    1. This study provides the first evidence of functional compensation whereby increased expression of CES3 restores intracellular cholesteryl ester hydrolytic activity and free cholesterol efflux in CES1-deficient cells. PMID: 22700792
    2. Studies indicate that CES3 mRNA isoform expression in several tissues, particularly in colon, trachea and in brain. PMID: 20422440
    3. CES3 seems to have a lower catalytic efficiency than the other two CESs for selected substrates. PMID: 19508181
    4. pharmacogenomic characterization of human carboxylesterase 1A1, 1A2, and 1A3 genes PMID: 18794728
  • 亞細胞定位：
    Endoplasmic reticulum lumen.
  • 蛋白家族：
    Type-B carboxylesterase/lipase family
  • 組織特異性：
    Expressed in liver, colon and small intestine.
  • 數據庫鏈接：

    HGNC: 1865

    OMIM: 605279

    KEGG: hsa:23491

    STRING: 9606.ENSP00000304782

    UniGene: Hs.268700



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