CERS4 Antibody
-
中文名稱:CERS4兔多克隆抗體
-
貨號:CSB-PA957321
-
規格:¥1100
-
圖片:
-
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA957321(CERS4 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
-
The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using CSB-PA957321(CERS4 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
-
Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-5: Human fetal liver tissue, HT29 cells, HUVEC cells, MCF7 cells, human hepatocellular carcinoma tissue, Primary antibody: CSB-PA957321(CERS4 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
-
-
其他:
產品詳情
-
Uniprot No.:
-
基因名:CERS4
-
別名:CERS4; LASS4; Ceramide synthase 4; CerS4; LAG1 longevity assurance homolog 4; Sphingosine N-acyltransferase CERS4
-
宿主:Rabbit
-
反應種屬:Human
-
免疫原:Synthetic peptide of Human CERS4
-
免疫原種屬:Homo sapiens (Human)
-
標記方式:Non-conjugated
-
抗體亞型:IgG
-
純化方式:Antigen affinity purification
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
-
產品提供形式:Liquid
-
應用范圍:ELISA,WB,IHC
-
推薦稀釋比:
Application Recommended Dilution ELISA 1:2000-1:5000 WB 1:500-1:2000 IHC 1:50-1:200 -
Protocols:
-
儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
-
用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
-
功能:Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor.
-
基因功能參考文獻:
- nine SNPs in the ceramide synthase 4 (CERS4) region were associated with circulating C23:0 levels (adjusted P<5x10-2) PMID: 29738550
- These results suggest that the phosphorylation of ceramide synthases may be a key regulatory point in the control of the distribution and levels of sphingolipids of various acyl-chain lengths. PMID: 26887952
- mRNA level of CerS4 is higher in cancerous cell lines and decreases following the induction of apoptosis. PMID: 25779024
- Co-expression of CerS2 with CerS4/CerS6 reversed the inhibitory effect of long chain ceramides on cell proliferation and the induction of apoptosis. we detected no effect on cell proliferation. PMID: 23538298
- The linkage and association of phospholipid transfer protein activity to LASS4 were studied. PMID: 21757428
顯示更多
收起更多
-
亞細胞定位:Endoplasmic reticulum membrane; Multi-pass membrane protein.
-
數據庫鏈接:
Most popular with customers
-
-
YWHAB Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC, IF, FC
Species Reactivity: Human, Mouse, Rat
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-